2. Gene
  3. TBC1D3B - TBC1 domain family member 3B Gene

TBC1D3B - TBC1 domain family member 3B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品

中文名称：TBC1 域家族成员 3B

种属: Homo sapiens

同用名: PRC17; TBC1D3I; TBC1D3L

基因 ID: 414059 | 基因类型: protein coding

关于 TBC1D3B

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:36,165,683-36,176,636 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele, 21 orthologues and 45 paralogues. Broad expression in testis (RPKM 19.5), skin (RPKM 8.9) and 23 other tissues.

功能概要

该基因编码的蛋白质类似于 TBC1 结构域家族成员 3。该蛋白质包含 TBC (Tre-2、Bub2p 和 Cdc16p) 结构域，存在于参与 RAB GTPase 信号转导和囊泡运输的蛋白质中。该基因的多个拷贝位于染色体 17q 上的趋化因子基因簇内。[RefSeq 提供，2009 年 4 月]

This gene encodes a protein that is similar to TBC1 domain family, member 3. This protein contains a TBC (Tre-2, Bub2p, and Cdc16p) domain, which is found in proteins involved in RAB GTPase signaling and vesicle trafficking. There are multiple copies of this gene located within a cluster of chemokine genes on chromosome 17q. [provided by RefSeq, Apr 2009]

TBC1D3B 基因产物(1)

mRNA Protein Name
NM_001001417.7 NP_001001417.6 TBC1 domain family member 3B

TBC1D3B 蛋白结构

RabGAP-TBC

RabGAP-TBC: Rab-GTPase-TBC domain (105 - 312)

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  • 549 a.a.
蛋白主名 其他名称

TBC1 domain family member 3B

Rab GTPase-activating protein PRC17 duplicate

关联疾病

疾病名称 别名
Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14243 TBC1D3B Human Pre-designed siRNA Set A Pre-designed Set / 否
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