1. Gene
  2. Elavl4 - ELAV like RNA binding protein 4 Gene

Elavl4 - ELAV like RNA binding protein 4 Gene

种属: Rattus norvegicus

同用名: HuD

基因 ID: 432358 | 基因类型: protein coding

关于 Elavl4

功能概要

Enables mRNA 3'-UTR binding activity and translation regulator activity. Involved in several processes, including cellular response to nerve growth factor stimulus; positive regulation of dendrite development; and posttranscriptional regulation of gene expression. Located in several cellular components, including growth cone; neuronal cell body; and polysomal ribosome. Is active in glutamatergic synapse. Biomarker of hypothyroidism; learning disability; sciatic neuropathy; and status epilepticus. Orthologous to human ELAVL4 (ELAV like RNA binding protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Elavl4 基因产物(1)

mRNA Protein Name
NM_001077651.2 NP_001071119.2 ELAV-like protein 4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mRNA 3'-UTR binding IDA
IDA: 通过直接分析推断
22736542 RGD
enables mRNA binding IDA
IDA: 通过直接分析推断
10436048 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
21389246 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in associative learning IEP
IEP: 通过表达模式推断
15519747 RGD
involved in cellular response to nerve growth factor stimulus IEP
IEP: 通过表达模式推断
9514914 RGD
involved in nervous system development IEP
IEP: 通过表达模式推断
9729424 RGD
involved in neuron differentiation IMP
IMP: 通过突变表型推断
9514914 RGD
involved in positive regulation of dendrite development IMP
IMP: 通过突变表型推断
22736542 RGD
involved in regeneration IEP
IEP: 通过表达模式推断
12957493 RGD
involved in regulation of mRNA stability IMP
IMP: 通过突变表型推断
22736542 RGD
involved in regulation of translation at postsynapse IDA
IDA: 通过直接分析推断
25692578 RGD
involved in regulation of translation at postsynapse IMP
IMP: 通过突变表型推断
25692578 RGD
involved in response to cocaine IEP
IEP: 通过表达模式推断
19014379 RGD
involved in response to endoplasmic reticulum stress IEP
IEP: 通过表达模式推断
23711134 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical dendrite IDA
IDA: 通过直接分析推断
15519747 RGD
located in cytoplasm IDA
IDA: 通过直接分析推断
15519747 RGD
located in dendrite IDA
IDA: 通过直接分析推断
14745023 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
25692578 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
25692578 RGD
located in growth cone IDA
IDA: 通过直接分析推断
15389607 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
12859688 RGD
located in nuclear envelope IDA
IDA: 通过直接分析推断
15389607 RGD
located in ribosome IDA
IDA: 通过直接分析推断
15519747 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ELAV-like protein 4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

ELAV like neuron-specific RNA binding protein 4

hu-antigen D

paraneoplastic encephalomyelitis antigen HuD

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Elavl4 NCBI NCBI:1996