1. Gene
  2. Cd274 - CD274 molecule Gene

Cd274 - CD274 molecule Gene

中文名称:CD274 分子

种属: Rattus norvegicus

同用名: Pdcd1lg1; RGD1566211

基因 ID: 499342 | 基因类型: protein coding

关于 Cd274

Primary_assembly 1: 227,116,649-227,134,450 forward strand.mRatBN7.2:CM026974.1

This gene has 1 transcript (splice variant), 102 orthologues, 8 paralogues and is associated with 55 phenotypes. Biased expression in Thymus (RPKM 12.9), Spleen (RPKM 58.3) and 9 other tissues.

功能概要

该基因编码的蛋白参与 T 细胞增殖的正向调节和细胞迁移的正向调节。位于细胞表面。牙周炎和先兆子痫的生物标志物。与人 CD274(CD274 分子)同源。 [由基因组资源联盟提供,2022 年 4 月]

Involved in positive regulation of T cell proliferation and positive regulation of cell migration. Located in cell surface. Biomarker of periodontitis and pre-eclampsia. Orthologous to human CD274 (CD274 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd274 基因产物(1)

mRNA Protein Name
NM_001191954.2 NP_001178883.1 programmed cell death 1 ligand 1 precursor

Cd274 蛋白结构

Ig

Ig: cl11960 (20 - 129)

Ig

Ig: cd00096 (35 - 39)

Ig

Ig: cd00096 (53 - 57)

Ig

Ig: cd00096 (96 - 100)

Ig

Ig: cd00096 (110 - 115)

Ig

Ig: cd00096 (122 - 125)

Ig

Ig: cl11960 (137 - 216)

Ig

Ig: cd00096 (149 - 153)

Ig

Ig: cd00096 (162 - 166)

Ig

Ig: cd00096 (193 - 197)

Ig

Ig: cd00096 (204 - 209)

  • 0
  • 100
  • 200
  • 290 a.a.
蛋白主名 其他名称

programmed cell death 1 ligand 1

重组 Cd274 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70814 PD-L1 Protein, Rat (221a.a, HEK293, His) D4AE25 (A18-T238) ≥95%
HY-P73364 PD-L1 Protein, Rat (HEK293, Fc) NP_001178883.1 (A18-T238) ≥95%
HY-P73365 PD-L1 Protein, Rat (HEK293, His) NP_001178883.1 (A18-T238) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd274 NCBI NCBI:29126
Canis familiaris Cd274 NCBI NCBI:484186
Macaca fascicularis Cd274 NCBI NCBI:102145573
Mus musculus Cd274 NCBI NCBI:60533
Macaca mulatta Cd274 NCBI NCBI:716043