2. Immunology/Inflammation
  3. PD-1/PD-L1
  4. MDX-1105

MDX-1105  (Synonyms: BMS-936559)

目录号: HY-P990623 纯度: ≥99.0%
COA 技术支持

MDX-1105 是 CHO 表达的人源抗体，靶向 B7-H1/PD-L1/CD274。MDX-1105 带有 huIgG4SP 型重链，其预测的分子量 (MW) 为 150 kDa。MDX-1105 的同型对照可参考 Human IgG4 kappa, Isotype Control (HY-P99003)。

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规格 价格 是否有货 数量
1 mg ￥3000
In-stock
5 mg ￥9000
In-stock
10 mg ￥14500
In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

MDX-1105 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

生物活性

MDX-1105 is a human antibody expressed in CHO that targets B7-H1/PD-L1/CD274. MDX-1105 has a huIgG4SP type heavy chain, and its predicted molecular weight (MW) is 150 kDa. The isotype control for MDX-1105 can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).

同型

Human IgG4 kappa
推荐同型对照抗体
IC50 & Target

B7-H1/PD-L1/CD274
应用

ELISA, FACS, Functional assay
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
  • Immobilized Human B7-H1/PD-L1/CD274, Fc Tag can bind MDX-1105. The EC50 for this effect is 16.78 ng/mL.
纯度 & 产品资料

纯度: ≥99.0%

COA (264 KB) SDS-PAGE (81 KB) SEC-HPLC (113 KB)

抗体抑制剂使用指南 (1152 KB)

MDX-1105 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MDX-1105BMS-936559MDX1105MDX 1105BMS936559BMS 936559PD-1/PD-L1PD-1/Programmed death-ligand 1Human AntibodyB7-H1/PD-L1/CD274 AntibodyInhibitorinhibitorinhibit

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Inquiry Information

产品名称：
MDX-1105
目录号：
HY-P990623
需求量：

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