2. Gene
  3. Srf - serum response factor Gene

Srf - serum response factor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: RGD1559787

基因 ID: 501099 | 基因类型: protein coding

关于 Srf

功能概要

Enables histone deacetylase binding activity and sequence-specific DNA binding activity. Involved in several processes, including cellular response to glucose stimulus; long-term memory; and positive regulation of transcription by glucose. Located in nucleus. Used to study hepatocellular carcinoma and hypertension. Human ortholog(s) of this gene implicated in cardiomyopathy and lymphangioleiomyomatosis. Orthologous to human SRF (serum response factor). [provided by Alliance of Genome Resources, Apr 2022]

Srf 基因产物(1)

mRNA Protein Name
NM_001109302.2 NP_001102772.1 serum response factor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone deacetylase binding IPI
IPI: 通过物理相互作用推断
12663674 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
23110084 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
16822834 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to glucose stimulus IEP
IEP: 通过表达模式推断
20655308 RGD
involved in long-term memory IMP
IMP: 通过突变表型推断
15816850 RGD
involved in negative regulation of cell migration IMP
IMP: 通过突变表型推断
16081871 RGD
involved in negative regulation of cell population proliferation IMP
IMP: 通过突变表型推断
16081871 RGD
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
16081871 RGD
involved in positive regulation of transcription by glucose IMP
IMP: 通过突变表型推断
20655308 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

serum response factor

serum response factor (c-fos serum response element-binding transcription factor)

相关产品

Clinical Phase
抗体抑制剂 (4)
目录号 产品名 作用方式
纯度 Phase
HY-P990068 Perenostobart 97.00% Phase 2
HY-P990024 Casdozokitug Inhibitor 96.49% Phase 2
HY-P99533 Urabrelimab Inhibitor 98.49% Phase 1
HY-P991061 CHS-114 Inhibitor / Phase 1
Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-13991 CCG-1423 99.88% 否
HY-108361 CCG-203971 Inhibitor 99.89% 否
HY-120855 CCG-100602 Inhibitor 99.29% 否
HY-111432 CCG-232601 Inhibitor 99.00% 否
HY-153078 MRTF/SRF-IN-1 Inhibitor 99.68% 否
HY-118748 Suprafenacine Inhibitor ≥98.0% 否
HY-130011 CCG-232964 Inhibitor / 否
HY-162904 BPU17 / 否
HY-162968 MRTF-A-IN-1 Inhibitor / 否
HY-162969 MRTF-A-IN-2 Inhibitor / 否
HY-RS13760 SRF Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17529 Srf Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23985 Srf Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Srf NCBI NCBI:6722
Mus musculus Srf NCBI NCBI:20807
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