2. Immunology/Inflammation
  3. Interleukin Related
  4. Urabrelimab

Urabrelimab  (Synonyms: SRF-231; SRF231)

目录号: HY-P99533

摩尔计算器

Urabrelimab (SRF231) 是一种完全人抗 CD47 单克隆抗体，可阻断 CD47-SIRP 相互作用。

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Urabrelimab Chemical Structure

Urabrelimab Chemical Structure

CAS No. : 2249722-58-3

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥3000
In-stock
5 mg ￥7800
In-stock
10 mg   询价  
50 mg   询价  

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Customer Review

Urabrelimab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Urabrelimab (SRF231) is a fully human anti-CD47 monoclonal antibody that blocks the CD47-SIRP interaction[1].

体外研究
(In Vitro)

Urabrelimab (SRF231) 在体外促进巨噬细胞介导的对几种血液原发肿瘤样本和细胞系的吞噬清除。Urabrelimab 增加 Raji 肿瘤细胞系靶细胞的吞噬作用，EC50 为 ~300 ng/mL[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Urabrelimab 相关抗体:
体内研究
(In Vivo)

Urabrelimab (SRF231) 在多发性骨髓瘤、弥漫性大 B 细胞淋巴瘤和伯基特淋巴瘤模型中作为单一药物和与调理抗体联合使用可导致显著的肿瘤生长抑制。在 Raji 异种移植模型中，单药处理可抑制 112% 的肿瘤生长[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Urabrelimab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Urabrelimab2249722-58-3SRF-231 SRF231SRF231SRF 231Interleukin RelatedILmyelomalymphomaRaji tumor cellInhibitorinhibitorinhibit

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