2. Gene
  3. NTM - neurotrimin Gene

NTM - neurotrimin Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：神经三肽

种属: Homo sapiens

同用名: HNT; NTRI; CEPU-1; IGLON2

基因 ID: 50863 | 基因类型: protein coding

关于 NTM

Cytogenetic location: 11q25 Genomic coordinates (GRCh38): 11:131,370,615-132,336,822 (from NCBI)

This gene has 23 transcripts (splice variants), 219 orthologues and 5 paralogues. Biased expression in brain (RPKM 12.0), lung (RPKM 3.5) and 5 other tissues.

功能概要

该基因编码含有糖基磷脂酰肌醇 (GPI) 的免疫球蛋白 (Ig) 结构域的 IgLON (LAMP、OBCAM、Ntm) 家族成员 - 锚定细胞粘附分子。编码的蛋白质可以通过嗜同性机制促进神经突生长和粘附。该基因与 11 号染色体上的相关家族成员阿片样物质结合蛋白/细胞粘附分子样 (OPCML) 密切相关。已发现该基因编码不同亚型的多个转录变体。[RefSeq 提供，2009 年 1 月]

This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. This gene is closely linked to a related family member, opioid binding protein/cell adhesion molecule-like (OPCML), on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009]

NTM 基因产物(19)

mRNA Protein Name
NM_001048209.2 NP_001041674.1 neurotrimin isoform 2 precursor
NM_001144058.2 NP_001137530.1 neurotrimin isoform 3 precursor
NM_001144059.3 NP_001137531.1 neurotrimin isoform 4 precursor
NM_001352001.2 NP_001338930.1 neurotrimin isoform 5 precursor
NM_001352002.2 NP_001338931.1 neurotrimin isoform 6 precursor
NM_001352003.2 NP_001338932.1 neurotrimin isoform 7 precursor
NM_001352004.2 NP_001338933.1 neurotrimin isoform 8 precursor
NM_001352005.2 NP_001338934.1 neurotrimin isoform 9 precursor
NM_001352006.2 NP_001338935.1 neurotrimin isoform 10
NM_001352007.2 NP_001338936.1 neurotrimin isoform 11
NM_001352008.2 NP_001338937.1 neurotrimin isoform 12
NM_001352009.2 NP_001338938.1 neurotrimin isoform 13
NM_001386964.1 NP_001373893.1 neurotrimin isoform 14
NM_001386965.1 NP_001373894.1 neurotrimin isoform 15
NM_001386966.1 NP_001373895.1 neurotrimin isoform 16
NM_001386967.1 NP_001373896.1 neurotrimin isoform 17
NM_001386968.1 NP_001373897.1 neurotrimin isoform 5
NM_001386969.1 NP_001373898.1 neurotrimin isoform 16
NM_016522.3 NP_057606.1 neurotrimin isoform 1 precursor

NTM 蛋白结构

I-set

I-set: Immunoglobulin I-set domain (38 - 132)

I-set

I-set: Immunoglobulin I-set domain (136 - 215)

I-set

I-set: Immunoglobulin I-set domain (230 - 310)

  • 0
  • 100
  • 200
  • 300
  • 344 a.a.
蛋白主名 其他名称

neurotrimin

IgLON family member 2

重组 NTM 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71154 Neurotrimin Protein, Human (283a.a, HEK293, His) Q9P121-3 (G34-L316) ≥95%
HY-P74701 Neurotrimin Protein, Human (312a.a, HEK293, His) Q9P121-1 (M1-G312) ≥95%
HY-P74702 Neurotrimin Protein, Human (HEK293, Fc) Q9P121-1 (M1-G312) ≥95%

关联疾病

疾病名称 别名
Juvenile Pilocytic Astrocytoma
Jacobsen Syndrome

Chromosome 11q Deletion Syndrome

Partial 11q Monosomy Syndrome

Jacobsen Distal 11q Deletion Syndrome

JBS

11q Partial Monosomy Syndrome

Chromosome 11q Deletion

11q Deletion

11q Monosomy

Deletion 11q

Monosomy 11q

Partial Monosomy 11q

11q Deletion Disorder

11q Deletion Syndrome

11q Terminal Deletion Disorder

11q- Deletion Syndrome

11q23 Deletion Disorder

Jacobsen Thrombocytopenia

11q Terminal Deletion Syndrome

Del(11)(Q23.3)

Del(11)(Qter)

Distal Deletion 11q

Distal Monosomy 11q

Monosomy 11qter

Telomeric Deletion 11q

Paris-Trousseau Thrombocytopenia
Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-148478 MMV688845 Inhibitor 99.35% 否
HY-RS09619 NTM Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus NTM VGNC VGNC:81966
Mus musculus NTM MGD MGI:2446259
Canis familiaris NTM VGNC VGNC:44005
Bos taurus NTM VGNC VGNC:32302
Macaca mulatta NTM VGNC VGNC:75425
Rattus norvegicus NTM RGD RGD:620958
Others NTM NCBI
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