1. Cell Cycle/DNA Damage
    Anti-infection
  2. Topoisomerase
    Bacterial
  3. VXc-​486

VXc-​486 

目录号: HY-12930
产品使用指南

VXc-486 是一种旋转酶 B 抑制剂,具有杀菌活性。VXc-486 能有效抑制结核分枝杆菌的多种药敏菌株和耐药菌株,MIC 分别为 0.03-0.30 μg/ml 和 0.08-5.48 μg/ml。

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VXc-​486 Chemical Structure

VXc-​486 Chemical Structure

CAS No. : 1384984-18-2

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Description

VXc-486 is a gyrase B inhibitor, with bactericidal activity. VXc-486 potently inhibits multiple drug-sensitive isolates and drug-resistant isolates of Mycobacterium tuberculosis, with MICs of 0.03 to 0.30 μg/ml and 0.08 to 5.48 μg/ml, respectively[1].

IC50 & Target

gyrase B[1]

Molecular Weight

428.46

Formula

C₂₁H₂₅FN₆O₃

CAS No.

1384984-18-2

SMILES

O=C(NC1=NC2=CC(C3=CN=C(C(C)(O)C)N=C3)=C(F)C([C@@H]4OCCC4)=C2N1)NCC

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
VXc-​486
目录号:
HY-12930
需求量:

VXc-​486

Cat. No.: HY-12930