ATP5F1C - ATP synthase F1 subunit gamma Gene

中文名称：ATP 合酶 F1 亚基γ

种属: Homo sapiens

同用名: ATP5C; ATP5C1; ATP5CL1

关于 ATP5F1C

功能概要

该基因编码线粒体 ATP 合酶的一个亚基。线粒体 ATP 合酶催化 ATP 合成，利用氧化磷酸化过程中跨内膜的质子电化学梯度。 ATP 合酶由两个连接的多亚基复合物组成：可溶性催化核心 F1 和跨膜成分 Fo，构成质子通道。线粒体 ATP 合酶的催化部分由 5 个不同的亚基 (alpha、beta、gamma、delta 和 epsilon) 组成，其化学计量为 3 个 alpha、3 个 beta 和其他 3 个的单一代表。质子通道由三个组成主要亚基 (a、b、c) 。该基因编码催化核心的γ亚基。已经鉴定出编码不同亚型的选择性剪接转录物变体。该基因在 14 号染色体上也有一个假基因。[RefSeq 提供，2008 年 7 月]

This gene encodes a subunit of mitochondrial ATP Synthase. Mitochondrial ATP Synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP Synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP Synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene also has a pseudogene on chromosome 14. [provided by RefSeq, Jul 2008]