1. Gene
  2. LAP3 - leucine aminopeptidase 3 Gene

LAP3 - leucine aminopeptidase 3 Gene

中文名称:亮氨酸氨肽酶 3

种属: Homo sapiens

同用名: LAP; PEPS; LAPEP; HEL-S-106

基因 ID: 51056 | 基因类型: protein coding

关于 LAP3

Cytogenetic location: 4p15.32 Genomic coordinates (GRCh38): 4:17,577,198-17,607,970 (from NCBI)

This gene has 11 transcripts (splice variants), 213 orthologues and 1 paralogue. Ubiquitous expression in appendix (RPKM 73.5), lymph node (RPKM 68.4) and 24 other tissues.

功能概要

预测启用肽酶活性。预计参与蛋白水解。位于胞质溶胶中;中体;和核质。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable peptidase activity. Predicted to be involved in proteolysis. Located in cytosol; midbody; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

LAP3 基因产物(1)

mRNA Protein Name
NM_015907.3 NP_056991.2 cytosol aminopeptidase

LAP3 蛋白结构

Peptidase_M17_N

Peptidase_M17_N: Cytosol aminopeptidase family, N-terminal domain (37 - 169)

Peptidase_M17

Peptidase_M17: Cytosol aminopeptidase family, catalytic domain (196 - 509)

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  • 519 a.a.
蛋白主名 其他名称

cytosol aminopeptidase

cysteinylglycine-S-conjugate dipeptidase

重组 LAP3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74780 LAP3 Protein, Human (HEK293, His) P28838/NP_056991.2 (M1-A519) ≥95%

关联疾病

疾病名称 别名
Bacterial Vaginosis

Vaginosis, Bacterial

Haverhill Fever

Streptobacillosis

Streptobacillary Rat-Bite Fever

Streptobacillary Fever

Rat-Bite Fever Due To Streptobacillus Moniliformis

Erythema Arthriticum Epidemicum

Epidemic Arthritic Erythema

Cholestasis

Obstruction Of Bile Duct

Bile Duct Obstruction

Bile Occlusion

Extrahepatic Biliary Obstruction

Extrahepatic Bile Duct Obstruction

Bile Stasis

Biliary Stasis

Obstructive Hyperbilirubinemia

Obstructed Jaundice

Bile Duct Obstructed

Bile Ductal Obstruction

Biliary Duct Obstruction

Obstructed Bile Ductal

Obstructed Biliary Duct

Obstructed Biliary Ductal

Jaundice Regurgitation

Obstructive Jaundice

Cholestatic Jaundice

Cholestatic Jaundice Syndrome

Syphilitic Meningitis

Syphilitic Aseptic Meningitis

Meningeal Syphilis

Meningitis, Syphilitic

Vaginitis

Infective Vaginitis

Inflammation Of Vagina

Colpitis

Vaginal Inflammation

Vaginitis Nos

Vaginal Disease

Vaginal Diseases

Vaginal Discharge
Specific Language Impairment

Language Impairment, Specific

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus LAP3 VGNC VGNC:78519
Mus musculus LAP3 MGD MGI:1914238
Bos taurus LAP3 VGNC VGNC:30786
Macaca mulatta LAP3 VGNC VGNC:97784
Canis familiaris LAP3 VGNC VGNC:42582
Rattus norvegicus LAP3 RGD RGD:1307985
Others LAP3 NCBI