2. Gene
  3. TRMO - tRNA methyltransferase O Gene

TRMO - tRNA methyltransferase O Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：tRNA 甲基转移酶 O

种属: Homo sapiens

同用名: NAP1; HSPC219; C9orf156

基因 ID: 51531 | 基因类型: protein coding

关于 TRMO

This gene has 6 transcripts (splice variants) and 173 orthologues. Ubiquitous expression in thyroid (RPKM 2.2), lymph node (RPKM 1.5) and 25 other tissues.

功能概要

启用 tRNA (腺嘌呤-N6-) -甲基转移酶活性。参与 tRNA 甲基化。 [由基因组资源联盟提供，2022 年 4 月]

Enables tRNA (adenine-N6-)-methyltransferase activity. Involved in tRNA methylation. [provided by Alliance of Genome Resources, Apr 2022]

TRMO 基因产物(7)

mRNA Protein Name
NM_001330725.2 NP_001317654.1 tRNA (adenine(37)-N6)-methyltransferase isoform 2
NM_001371657.1 NP_001358586.1 tRNA (adenine(37)-N6)-methyltransferase isoform 1
NM_001371658.1 NP_001358587.1 tRNA (adenine(37)-N6)-methyltransferase isoform 3
NM_001371659.1 NP_001358588.1 tRNA (adenine(37)-N6)-methyltransferase isoform 4
NM_001371660.1 NP_001358589.1 tRNA (adenine(37)-N6)-methyltransferase isoform 2
NM_001371661.1 NP_001358590.1 tRNA (adenine(37)-N6)-methyltransferase isoform 2
NM_016481.5 NP_057565.3 tRNA (adenine(37)-N6)-methyltransferase isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables tRNA (L-threonylcarbamoyladenosine(37)-C2) methyltransferase activity IDA
IDA: 通过直接分析推断
25063302 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in tRNA methylation IDA
IDA: 通过直接分析推断
25063302 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TRMO 蛋白结构

UPF0066

UPF0066: Uncharacterised protein family UPF0066 (43 - 164)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 441 a.a.
蛋白主名 其他名称

tRNA (adenine(37)-N6)-methyltransferase

Nef (lentivirus myristoylated factor) associated protein 1

TRMO 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TRMO Q9BU70 SPATC1L Homo sapiens Q9H0A9-2
Validated Y2H
32296183
种属内
TRMO Q9BU70 SPATC1L Homo sapiens Q9H0A9-2
Y2H Prey Pooling
32296183
种属内
TRMO Q9BU70 SPATC1L Homo sapiens Q9H0A9-2
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Arthrogryposis, Distal, Type 6

Distal Arthrogryposis Type 6

DA6

Arthrogryposis-Like Hand Anomaly-Sensorineural Deafness Syndrome

Arthrogryposis And Sensorineural Deafness

Familial Hand Abnormality And Sensori-Neural Deafness

Arthrogryposis-Like Hand Anomaly And Sensorineural Deafness

Arthrogryposis-Like Hand Anomaly-Sensorineural Hearing Loss Syndrome
Thiamine-Responsive Megaloblastic Anemia Syndrome

TRMA

Rogers Syndrome

Thiamine-Responsive Myelodysplasia

Thiamine-Responsive Anemia Syndrome

Thiamine Metabolism Dysfunction Syndrome 1

Thmd1

Megaloblastic Anemia, Thiamine-Responsive, With Diabetes Mellitus And Sensorineural Deafness

Thiamine-Responsive Megaloblastic Anemia With Diabetes Mellitus And Sensorineural Deafness

Thiamine Responsive Megaloblastic Anemia Syndrome

Megaloblastic Anemia Thiamine-Responsive With Diabetes Mellitus And Sensorineural Deafness

Thiamine-Responsive Megaloblastic Anemia

Thiamine-Responsive Anaemia Syndrome

Thiamine-Responsive Megaloblastic Anaemia Syndrome

Thiamine-Responsive Megaloblastic Anaemia With Diabetes Mellitus And Sensorineural Deafness

Thiamine-Responsive Megaloblastic Anemia With Diabetes Mellitus And Sensorineural Hearing Loss
Cleft Palate, Isolated

Cleft Palate

Isolated Cleft Palate

CPI

Cp

Palatoschisis

Cleft Palate Isolated

Uranostaphyloschisis

Congenital Fissure Of Palate

Cleft Of Secondary Palate
Galloway-Mowat Syndrome

Galloway Mowat Syndrome

Galloway Syndrome

Hiatal Hernia-Microcephaly-Nephrosis, Galloway Type

Microcephaly Nephrosis Syndrome

Microcephaly, Hiatal Hernia, And Nephrotic Syndrome

Nephrosis Neuronal Dysmigration Syndrome

Microcephaly-Hiatus Hernia-Nephrotic Syndrome

Nephrosis-Neuronal Dysmigration Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15085 TRMO Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta TRMO VGNC VGNC:79907
Mus musculus TRMO MGD MGI:1922003
Bos taurus TRMO VGNC VGNC:36364
Rattus norvegicus TRMO RGD RGD:1305420
Felis catus TRMO VGNC VGNC:66564
Canis familiaris TRMO VGNC VGNC:47849
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z