2. Gene
  3. MBIP - MAP3K12 binding inhibitory protein 1 Gene

MBIP - MAP3K12 binding inhibitory protein 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：MAP3K12 结合抑制蛋白 1

种属: Homo sapiens

基因 ID: 51562 | 基因类型: protein coding

关于 MBIP

Cytogenetic location: 14q13.3 Genomic coordinates (GRCh38): 14:36,298,564-36,320,637 (from NCBI)

This gene has 10 transcripts (splice variants), 197 orthologues and 3 paralogues. Broad expression in thyroid (RPKM 34.1), lung (RPKM 32.4) and 24 other tissues.

功能概要

实现相同的蛋白质结合活性和蛋白激酶抑制剂活性。参与组蛋白 H3 乙酰化； JNK 级联的正调控；和基因表达的正调控。位于胞质溶胶中；核仁;和核质。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity and protein kinase inhibitor activity. Involved in histone H3 acetylation; positive regulation of JNK cascade; and positive regulation of gene expression. Located in cytosol; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

MBIP 基因产物(3)

mRNA Protein Name
NM_001144891.2 NP_001138363.1 MAP3K12-binding inhibitory protein 1 isoform 2
NM_001308110.2 NP_001295039.1 MAP3K12-binding inhibitory protein 1 isoform 3
NM_016586.3 NP_057670.2 MAP3K12-binding inhibitory protein 1 isoform 1
蛋白主名 其他名称

MAP3K12-binding inhibitory protein 1

MAPK upstream kinase-binding inhibitory protein

重组 MBIP 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70921 MBIP Protein, Human (His) Q9NS73 (M1-P344) ≥95%

关联疾病

疾病名称 别名
Bronchus Adenoma

Bronchial Adenoma

Adenoma Of The Bronchus
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08187 MBIP Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus MBIP MGD MGI:1918320
Bos taurus MBIP VGNC VGNC:31279
Felis catus MBIP VGNC VGNC:80921
Canis familiaris MBIP VGNC VGNC:43055
Macaca mulatta MBIP VGNC VGNC:74543
Rattus norvegicus MBIP RGD RGD:1306310
Others MBIP NCBI
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