2. Gene
  3. FKBP7 - FKBP prolyl isomerase 7 Gene

FKBP7 - FKBP prolyl isomerase 7 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：FKBP 脯氨酰异构酶 7

种属: Homo sapiens

同用名: FKBP23; PPIase

基因 ID: 51661 | 基因类型: protein coding

关于 FKBP7

Cytogenetic location: 2q31.2 Genomic coordinates (GRCh38): 2:178,463,664-178,478,600 (from NCBI)

This gene has 12 transcripts (splice variants), 210 orthologues and 18 paralogues. Broad expression in ovary (RPKM 13.6), endometrium (RPKM 9.0) and 21 other tissues.

功能概要

该基因编码的蛋白质属于 FKBP 型肽基-脯氨酰顺/反异构酶 (PPIase) 家族。该家族的成员表现出 PPIase 活性并充当分子伴侣。小鼠中的一种类似蛋白质位于内质网中并结合钙。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. Members of this family exhibit PPIase activity and function as molecular chaperones. A similar protein in mouse is located in the endoplasmic reticulum and binds calcium. [provided by RefSeq, Jul 2008]

FKBP7 基因产物(3)

mRNA Protein Name
NM_001135212.2 NP_001128684.1 peptidyl-prolyl cis-trans isomerase FKBP7 isoform b precursor
NM_001410972.1 NP_001397901.1 peptidyl-prolyl cis-trans isomerase FKBP7 isoform c precursor
NM_181342.3 NP_851939.1 peptidyl-prolyl cis-trans isomerase FKBP7 isoform a precursor

FKBP7 蛋白结构

FKBP_C

FKBP_C: FKBP-type peptidyl-prolyl cis-trans isomerase (48 - 141)

EF-hand_7

EF-hand_7: EF-hand domain pair (153 - 215)

  • 0
  • 100
  • 200
  • 222 a.a.
蛋白主名 其他名称

peptidyl-prolyl cis-trans isomerase FKBP7

23 kDa FK506-binding protein

FKBP7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
FKBP7 Q9Y680 NPFFR2 Homo sapiens Q9Y5X5-3
Y2H Prey Pooling
32296183
种属内
FKBP7 Q9Y680 NPFFR2 Homo sapiens Q9Y5X5-3
Y2H Array
32296183
种属内
FKBP7 Q9Y680 SGTA Homo sapiens O43765
Y2H Prey Pooling
25416956
种属内
FKBP7 Q9Y680 SGTA Homo sapiens O43765
Y2H Prey Pooling
32296183
种属内
FKBP7 Q9Y680 SGTA Homo sapiens O43765
Y2H Array
32296183
种属内
FKBP7 Q9Y680 PEX19 Homo sapiens P40855
Y2H Array
25416956
种属内
FKBP7 Q9Y680 TMEM108 Homo sapiens Q6UXF1
Y2H Array
32296183
种属内
FKBP7 Q9Y680 TMEM108 Homo sapiens Q6UXF1
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 FKBP7 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70949 FKBP7 Protein, Human (HEK293, His) Q9Y680-2 (Q24-L222) ≥95%
HY-P76932 FKBP7 Protein, Human (HEK293, Fc) Q9Y680-2 (Q24-Q218) ≥95%

关联疾病

疾病名称 别名
Osteogenesis Imperfecta, Type Xi

Osteogenesis Imperfecta Type 11

OI11

Osteogenesis Imperfecta Type Xi

Oi, Type Xi

Osteogenesis Imperfecta 11

Oi Type Xi

Oi-Xi
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04967 FKBP7 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20407 Fkbp7 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26916 Fkbp7 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus FKBP7 RGD RGD:1305293
Macaca mulatta FKBP7 VGNC VGNC:72667
Felis catus FKBP7 VGNC VGNC:62283
Bos taurus FKBP7 VGNC VGNC:29026
Mus musculus FKBP7 MGD MGI:1336879
Canis familiaris FKBP7 VGNC VGNC:40893
Others FKBP7 NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z