2. Gene
  3. Hnrnpu - heterogeneous nuclear ribonucleoprotein U Gene

Hnrnpu - heterogeneous nuclear ribonucleoprotein U Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: SAFA; Hnrpu; Sp120; hnRNP U

基因 ID: 51810 | 基因类型: protein coding

关于 Hnrnpu

功能概要

Enables RNA polymerase II C-terminal domain binding activity; nucleic acid binding activity; and promoter-specific chromatin binding activity. Involved in several processes, including RNA localization to chromatin; cellular response to leukemia inhibitory factor; and regulation of gene expression. Acts upstream of or within with a positive effect on mRNA metabolic process. Acts upstream of or within cardiac muscle cell development. Located in inactive sex chromosome and nucleus. Part of ribonucleoprotein complex. Is expressed in several structures, including branchial arch; future brain; limb primordium; tail bud; and unsegmented mesenchyme. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 54. Orthologous to human HNRNPU (heterogeneous nuclear ribonucleoprotein U). [provided by Alliance of Genome Resources, Apr 2022]

Hnrnpu 基因产物(1)

mRNA Protein Name
NM_016805.3 NP_058085.2 heterogeneous nuclear ribonucleoprotein U
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA binding IDA
IDA: 通过直接分析推断
20833368 MGI
enables RNA binding IPI
IPI: 通过物理相互作用推断
25921091 MGI
enables RNA polymerase II C-terminal domain binding IDA
IDA: 通过直接分析推断
21235343 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
18332112 MGI
enables lncRNA binding IDA
IDA: 通过直接分析推断
25921091 MGI
enables promoter-specific chromatin binding IDA
IDA: 通过直接分析推断
21235343 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18495661 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
21235343 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in RNA localization to chromatin IMP
IMP: 通过突变表型推断
20833368 MGI
involved in adaptive thermogenesis IMP
IMP: 通过突变表型推断
28784777 MGI
acts upstream of or within cardiac muscle cell development IMP
IMP: 通过突变表型推断
26039991 MGI
involved in cellular response to leukemia inhibitory factor IDA
IDA: 通过直接分析推断
21235343 MGI
involved in circadian regulation of gene expression IDA
IDA: 通过直接分析推断
18332112 MGI
involved in dendritic transport of messenger ribonucleoprotein complex IDA
IDA: 通过直接分析推断
15312650 MGI
involved in dendritic transport of messenger ribonucleoprotein complex IMP
IMP: 通过突变表型推断
15312650 MGI
involved in dosage compensation by inactivation of X chromosome IMP
IMP: 通过突变表型推断
20833368 MGI
acts upstream of or within erythrocyte differentiation IMP
IMP: 通过突变表型推断
28636939 MGI
acts upstream of or within positive effect mRNA metabolic process IMP
IMP: 通过突变表型推断
25921091 MGI
involved in negative regulation of stem cell differentiation IMP
IMP: 通过突变表型推断
21235343 MGI
involved in positive regulation of brown fat cell differentiation IMP
IMP: 通过突变表型推断
28784777 MGI
involved in positive regulation of stem cell proliferation IMP
IMP: 通过突变表型推断
20833368 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
22162999 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
21235343 MGI
involved in random inactivation of X chromosome IMP
IMP: 通过突变表型推断
25915022 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in inactive sex chromosome IDA
IDA: 通过直接分析推断
20833368 MGI
located in nucleus IDA
IDA: 通过直接分析推断
18332112 MGI
part of ribonucleoprotein complex IDA
IDA: 通过直接分析推断
25921091 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

heterogeneous nuclear ribonucleoprotein U

heterogenous nuclear ribonucleoprotein U

nuclear matrix protein sp120

scaffold attachment factor A

Hnrnpu 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Hnrnpu Q8VEK3 Smarca4 Mus musculus Q3TKT4
PLA
22162999
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06278 HNRNPU Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21138 Hnrnpu Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27656 Hnrnpu Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hnrnpu NCBI NCBI:3192
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