2. Gene
  3. Tet1 - tet methylcytosine dioxygenase 1 Gene

Tet1 - tet methylcytosine dioxygenase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: LCX; Cxxc6; mKIAA1676; D10Ertd17e; 2510010B09Rik

基因 ID: 52463 | 基因类型: protein coding

关于 Tet1

功能概要

Enables methylcytosine dioxygenase activity. Involved in several processes, including dendrite morphogenesis; inner cell mass cell differentiation; and protein O-linked glycosylation. Acts upstream of or within DNA demethylation; regulation of DNA methylation; and regulation of genetic imprinting. Located in nucleus. Is expressed in several structures, including brain; early conceptus; embryo ectoderm; lower urogenital tract; and reproductive system. Orthologous to human TET1 (tet methylcytosine dioxygenase 1). [provided by Alliance of Genome Resources, Apr 2022]

Tet1 基因产物(4)

mRNA Protein Name
NM_001253857.2 NP_001240786.1 methylcytosine dioxygenase TET1 isoform 1
NM_001406381.1 NP_001393310.1 methylcytosine dioxygenase TET1 isoform 3
NM_001406382.1 NP_001393311.1 methylcytosine dioxygenase TET1 isoform 5
NM_001406383.1 NP_001393312.1 methylcytosine dioxygenase TET1 isoform 4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 5-methylcytosine dioxygenase activity IDA
IDA: 通过直接分析推断
19372391 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
31467272 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21490601 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in dendrite morphogenesis IMP
IMP: 通过突变表型推断
26711116 MGI
acts upstream of or within epigenetic programing of male pronucleus IMP
IMP: 通过突变表型推断
24291790 MGI
acts upstream of or within inner cell mass cell differentiation IMP
IMP: 通过突变表型推断
20639862 MGI
involved in inner cell mass cell differentiation IMP
IMP: 通过突变表型推断
19372391 MGI
acts upstream of or within positive regulation of gene expression via chromosomal CpG island demethylation IDA
IDA: 通过直接分析推断
20639862 MGI
involved in positive regulation of gene expression via chromosomal CpG island demethylation IGI
IGI: 通过遗传相互作用推断
31467272 MGI
acts upstream of or within positive regulation of gene expression via chromosomal CpG island demethylation IMP
IMP: 通过突变表型推断
21295276 MGI
involved in positive regulation of gene expression via chromosomal CpG island demethylation IMP
IMP: 通过突变表型推断
19372391 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
23352454 MGI
involved in protein O-linked glycosylation IMP
IMP: 通过突变表型推断
23352454 MGI
involved in stem cell population maintenance IMP
IMP: 通过突变表型推断
19372391 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
19372391 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

methylcytosine dioxygenase TET1

CXXC finger 6

CXXC-type zinc finger protein 6

ten-eleven translocation 1 gene protein homolog

tet oncogene 1

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-W396714 Succinic acid sodium Inhibitor / 否
Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-111558 Bobcat339 Inhibitor 99.44% 否
HY-111558A Bobcat339 hydrochloride Inhibitor 99.59% 否
HY-12303 OAC1 Activator 99.56% 否
HY-122258 NSC-370284 Inhibitor 99.27% 否
HY-402410 TETi76 Inhibitor 97.49% 否
HY-120395 UC-514321 Inhibitor ≥98.0% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tet1 NCBI NCBI:80312
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