2. Gene
  3. E2f7 - E2F transcription factor 7 Gene

E2f7 - E2F transcription factor 7 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: E2F-7; D10Ertd739e; A630014C11Rik

基因 ID: 52679 | 基因类型: protein coding

关于 E2f7

功能概要

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including hepatocyte differentiation; regulation of cell cycle process; and trophoblast giant cell differentiation. Acts upstream of or within negative regulation of cell population proliferation and regulation of transcription, DNA-templated. Located in nucleus. Is expressed in brain; embryo mesenchyme; and genitourinary system. Orthologous to human E2F7 (E2F transcription factor 7). [provided by Alliance of Genome Resources, Apr 2022]

E2f7 基因产物(2)

mRNA Protein Name
NM_001358560.2 NP_001345489.1 transcription factor E2F7
NM_178609.6 NP_848724.2 transcription factor E2F7
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
12893818 MGI
enables DNA-binding transcription factor activity IMP
IMP: 通过突变表型推断
22516201 MGI
enables DNA-binding transcription repressor activity IDA
IDA: 通过直接分析推断
22180533 MGI
enables DNA-binding transcription repressor activity IMP
IMP: 通过突变表型推断
22516201 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
12893818 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
22180533 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
12893818 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
22903062 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in chorionic trophoblast cell differentiation IMP
IMP: 通过突变表型推断
22516201 MGI
involved in hepatocyte differentiation IMP
IMP: 通过突变表型推断
23064266 MGI
involved in negative regulation of G1/S transition of mitotic cell cycle IDA
IDA: 通过直接分析推断
22180533 MGI
acts upstream of or within negative regulation of cell population proliferation IDA
IDA: 通过直接分析推断
12893818 MGI
involved in negative regulation of cytokinesis IMP
IMP: 通过突变表型推断
23064266 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12893818 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
22516201 MGI
involved in placenta development IMP
IMP: 通过突变表型推断
22516201 MGI
involved in positive regulation of DNA endoreduplication IMP
IMP: 通过突变表型推断
23064266 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12893818 MGI
involved in sprouting angiogenesis IMP
IMP: 通过突变表型推断
22903062 MGI
involved in trophoblast giant cell differentiation IMP
IMP: 通过突变表型推断
23064266 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
12893818 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor E2F7

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04116 E2F7 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18926 E2f7 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25416 E2f7 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens E2f7 NCBI NCBI:144455
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