IL20RA - interleukin 20 receptor subunit alpha Gene

中文名称：白介素 20 受体亚基 α

种属: Homo sapiens

同用名: CRF2-8; IL-20R1; IL-20RA; IL-20R-alpha

关于 IL20RA

功能概要

该基因编码 II 型细胞因子受体家族的成员。编码的蛋白质是白细胞介素 20 受体的一个亚基，白细胞介素 20 是一种可能参与表皮功能的细胞因子。白细胞介素 20 受体是由编码蛋白和白细胞介素 20 受体 β 组成的异二聚体复合物。该基因和白细胞介素 20 受体 β 在皮肤中高度表达，并在牛皮癣中上调。可变剪接导致多个转录本变体。[RefSeq 提供，2013 年 7 月]

This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]