2. Gene
  3. KCTD5 - potassium channel tetramerization domain containing 5 Gene

KCTD5 - potassium channel tetramerization domain containing 5 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含钾通道四聚结构域 5

种属: Homo sapiens

基因 ID: 54442 | 基因类型: protein coding

关于 KCTD5

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:2,682,523-2,709,030 (from NCBI)

This gene has 5 transcripts (splice variants), 219 orthologues and 3 paralogues. Ubiquitous expression in colon (RPKM 15.1), esophagus (RPKM 11.8) and 25 other tissues.

功能概要

实现相同的蛋白质结合活性。预计参与蛋白酶体介导的泛素依赖性蛋白质分解代谢过程。位于胞质溶胶中。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

KCTD5 基因产物(1)

mRNA Protein Name
NM_018992.4 NP_061865.1 BTB/POZ domain-containing protein KCTD5
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
27152988 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
17239418 GOA
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
23209302 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
18573101 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

KCTD5 蛋白结构

BTB_2

BTB_2: BTB/POZ domain (46 - 135)

  • 0
  • 100
  • 200
  • 234 a.a.
蛋白主名 其他名称

BTB/POZ domain-containing protein KCTD5

potassium channel tetramerisation domain containing 5

KCTD5 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
KCTD5 Q9NXV2 GIT2 Homo sapiens Q14161
Y2H Array
21988832
种属内
KCTD5 Q9NXV2 KCTD5 Homo sapiens Q9NXV2
EM
27152988
种属内
KCTD5 Q9NXV2 KCTD5 Homo sapiens Q9NXV2
GMS
27152988
种属内
KCTD5 Q9NXV2 CD1A Homo sapiens P06126
Y2H Array
21988832
种属内
KCTD5 Q9NXV2 Rep78 Adeno-associated virus 2 Q89268
IF
17239418
种属内
KCTD5 Q9NXV2 Rep78 Adeno-associated virus 2 Q89268
Anti Bait CoIP
17239418
种属间
KCTD5 Q9NXV2 Rep68 Adeno-associated virus 2 P03132
Anti Bait CoIP
17239418
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Scalp-Ear-Nipple Syndrome

Finlay-Marks Syndrome

Sen Syndrome

SENS

Scalp Ear Nipple Syndrome

Hereditary Syndrome Of Lumpy Scalp, Odd Ears And Rudimentary Nipples

Hereditary Syndrome Of Lumpy Scalp, Odd Ears, And Rudimentary Nipples

Indian Childhood Cirrhosis
Branchiooculofacial Syndrome

Branchio-Oculo-Facial Syndrome

BOFS

Bof Syndrome

Hemangiomatous Branchial Clefts-Lip Pseudocleft Syndrome

Lip Pseudocleft-Hemangiomatous Branchial Cyst Syndrome

Branchial Clefts With Characteristic Facies, Growth Retardation, Imperforate Nasolacrimal Duct, And Premature Aging

Branchial Clefts With Characteristic Facies Growth Retardation Imperforate Nasolacrimal Duct And Premature Aging

Bofs Syndrome

Lip Pseudocleft-Hemagiomatous Branchial Cyst Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07197 KCTD5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21614 Kctd5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28132 Kctd5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta KCTD5 VGNC VGNC:73876
Mus musculus KCTD5 MGD MGI:1916509
Canis familiaris KCTD5 VGNC VGNC:42309
Felis catus KCTD5 VGNC VGNC:97472
Rattus norvegicus KCTD5 RGD RGD:1304990
Bos taurus KCTD5 VGNC VGNC:30513
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