PCDH18 - protocadherin 18 Gene

中文名称：原钙粘蛋白 18

种属: Homo sapiens

同用名: PCDH68L

关于 PCDH18

功能概要

该基因属于原钙粘蛋白基因家族，是钙粘蛋白超家族的一个亚家族。该基因编码的蛋白质包含 6 个细胞外钙粘蛋白结构域、一个跨膜结构域和一个不同于经典钙粘蛋白的细胞质尾部。虽然其具体功能尚未确定，但钙粘蛋白相关神经元受体被认为在大脑中特定细胞间连接的建立和功能中发挥作用。[RefSeq 提供，2008 年 7 月]

This gene belongs to the protocadherin gene family, a subfamily of the Cadherin superfamily. This gene encodes a protein which contains 6 extracellular Cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical Cadherins. Although its specific function is undetermined, the cadherin-related neuronal receptor is thought to play a role in the establishment and function of specific cell-cell connections in the brain. [provided by RefSeq, Jul 2008]