1. Gene
  2. FAIM - Fas apoptotic inhibitory molecule Gene

FAIM - Fas apoptotic inhibitory molecule Gene

中文名称:Fas 凋亡抑制分子

种属: Homo sapiens

同用名: FAIM1

基因 ID: 55179 | 基因类型: protein coding

关于 FAIM

Cytogenetic location: 3q22.3 Genomic coordinates (GRCh38): 3:138,608,771-138,633,376 (from NCBI)

This gene has 9 transcripts (splice variants) and 276 orthologues. Ubiquitous expression in fat (RPKM 4.9), thyroid (RPKM 4.0) and 25 other tissues.

功能概要

由该基因编码的蛋白质可防止死亡受体触发的细胞凋亡并调节 B 细胞信号传导和分化。已发现该基因编码不同亚型的几种转录变体。[RefSeq 提供,2011 年 7 月]

The protein encoded by this gene protects against death receptor-triggered Apoptosis and regulates B-cell signaling and differentiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

FAIM 基因产物(4)

mRNA Protein Name
NM_001033030.2 NP_001028202.1 fas apoptotic inhibitory molecule 1 isoform a
NM_001033031.2 NP_001028203.1 fas apoptotic inhibitory molecule 1 isoform b
NM_001033032.2 NP_001028204.1 fas apoptotic inhibitory molecule 1 isoform c
NM_018147.4 NP_060617.1 fas apoptotic inhibitory molecule 1 isoform c
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

FAIM 蛋白结构

FAIM1

FAIM1: Fas apoptotic inhibitory molecule (FAIM1) (1 - 176)

  • 0
  • 100
  • 179 a.a.
蛋白主名 其他名称

fas apoptotic inhibitory molecule 1

FAIM 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
FAIM Q9NVQ4 WDR47 Homo sapiens O94967 33961781
种属内
FAIM Q9NVQ4 SPRY2 Homo sapiens O43597 25416956
种属内
FAIM Q9NVQ4 SPRY2 Homo sapiens O43597 25416956
种属内
FAIM Q9NVQ4 SPRY2 Homo sapiens O43597 25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Osteogenesis Imperfecta, Type X

Osteogenesis Imperfecta Type 10

OI10

Osteogenesis Imperfecta Type X

Oi, Type X

Osteogenesis Imperfecta 10

Oi Type X

Oi-X

Milker'S Nodule

Poxviridae Infections

Milker Nodule

Milkers' Node

Paravaccinia

Pseudocowpox

Milker'S Nodes

Kwashiorkor

Kwashiokor

Nutritional Edema With Dyspigmentation Of Skin And Hair

Nutritional Oedema With Dyspigmentation Of Skin And/Or Hair

Contagious Pustular Dermatitis

Ecthyma, Contagious

Orf

Ecthyma Contagiosum

Scabby Mouth

Sheep Pox

Thistle Disease

Contagious Pustular Dermatosis

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta FAIM VGNC VGNC:72297
Mus musculus FAIM MGD MGI:1344387
Rattus norvegicus FAIM RGD RGD:620572
Felis catus FAIM VGNC VGNC:102694
Bos taurus FAIM VGNC VGNC:28709
Canis familiaris FAIM VGNC VGNC:40570