1. Gene
  2. APOM - apolipoprotein M Gene

APOM - apolipoprotein M Gene

中文名称:载脂蛋白 M

种属: Homo sapiens

同用名: G3a; NG20; apo-M; HSPC336

基因 ID: 55937 | 基因类型: protein coding

关于 APOM

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:31,652,404-31,658,210 (from NCBI)

This gene has 3 transcripts (splice variants), 1 gene allele and 111 orthologues. Biased expression in liver (RPKM 122.3), kidney (RPKM 73.7) and 1 other tissue.

功能概要

由该基因编码的蛋白质是一种载脂蛋白,是脂质运载蛋白家族的成员。它被发现与高密度脂蛋白有关,并在较小程度上与低密度脂蛋白和富含甘油三酯的脂蛋白有关。编码的蛋白质通过质膜分泌,但仍与膜结合,参与脂质转运。交替剪接导致该基因的编码和非编码变体。[RefSeq 提供,2012 年 1 月]

The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012]

APOM 基因产物(2)

mRNA Protein Name
NM_001256169.2 NP_001243098.1 apolipoprotein M isoform 2
NM_019101.3 NP_061974.2 apolipoprotein M isoform 1

APOM 蛋白结构

ApoM

ApoM: ApoM domain (1 - 186)

  • 0
  • 100
  • 188 a.a.
蛋白主名 其他名称

apolipoprotein M

NG20-like protein

重组 APOM 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7536 Apolipoprotein M/APOM Protein, Human (HEK293, His) O95445 (C23-N188) ≥95%

关联疾病

疾病名称 别名
Fetal Macrosomia
Maturity-Onset Diabetes Of The Young, Type 3

Maturity-Onset Diabetes Of The Young Type 3

MODY3

Mody, Type Iii

Mody Type 3

Mody, Type 3

Maturity-Onset Diabetes Of The Young 3

Mody-3

Diabetes Of The Young, Maturity-Onset, Type 3

Maturity-Onset Diabetes Of The Young

MODY

Maturity Onset Diabetes Mellitus In Young

Mason-Type Diabetes

Mason Type Diabetes

Maturity Onset Diabetes Of The Young

Mody Syndrome

Diabetes Of The Young, Maturity-Onset

Diabetes Mellitus

Diabetes

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus APOM MGD MGI:1930124
Bos taurus APOM VGNC VGNC:26034
Rattus norvegicus APOM RGD RGD:620773
Felis catus APOM VGNC VGNC:59855
Canis familiaris APOM VGNC VGNC:38008
Macaca mulatta APOM VGNC VGNC:69825
Others APOM NCBI