1. Gene
  2. CRTAM - cytotoxic and regulatory T cell molecule Gene

CRTAM - cytotoxic and regulatory T cell molecule Gene

中文名称:细胞毒性和调节性 T 细胞分子

种属: Homo sapiens

同用名: CD355

基因 ID: 56253 | 基因类型: protein coding

关于 CRTAM

Cytogenetic location: 11q24.1 Genomic coordinates (GRCh38): 11:122,838,500-122,872,643 (from NCBI)

This gene has 3 transcripts (splice variants), 203 orthologues and 14 paralogues. Biased expression in lymph node (RPKM 4.2), spleen (RPKM 1.7) and 11 other tissues.

功能概要

CRTAM 基因在 CD4 (参见 MIM 186940) 阳性和 CD8 (参见 CD8A;MIM 186910) 阳性 T 细胞中上调,并编码具有 V 和 C1 样 Ig 结构域的 I 型跨膜蛋白 (Yeh 等人,2008 [ PubMed 18329370]) .[OMIM 提供,2009 年 2 月]

The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains (Yeh et al., 2008 [PubMed 18329370]).[supplied by OMIM, Feb 2009]

CRTAM 基因产物(2)

mRNA Protein Name
NM_001304782.2 NP_001291711.1 cytotoxic and regulatory T-cell molecule isoform 2 precursor
NM_019604.4 NP_062550.2 cytotoxic and regulatory T-cell molecule isoform 1 precursor

CRTAM 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (20 - 113)

C2-set_2

C2-set_2: CD80-like C2-set immunoglobulin domain (129 - 206)

  • 0
  • 100
  • 200
  • 300
  • 393 a.a.
蛋白主名 其他名称

cytotoxic and regulatory T-cell molecule

class-I MHC-restricted T-cell-associated molecule

重组 CRTAM 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7855 CRTAM/CD355 Protein, Human (HEK293, His) O95727 (S18-S286) ≥95%

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta CRTAM VGNC VGNC:84883
Mus musculus CRTAM MGD MGI:1859822
Bos taurus CRTAM VGNC VGNC:27726
Canis familiaris CRTAM VGNC VGNC:39630
Felis catus CRTAM VGNC VGNC:61190
Rattus norvegicus CRTAM RGD RGD:1304602
Macaca fascicularis CRTAM NCBI
Others CRTAM NCBI