1. Gene
  2. Aatf - apoptosis antagonizing transcription factor Gene

Aatf - apoptosis antagonizing transcription factor Gene

种属: Mus musculus

同用名: Trb; Che-1; 4933415H02Rik; 5830465M17Rik

基因 ID: 56321 | 基因类型: protein coding

关于 Aatf

功能概要

Predicted to enable leucine zipper domain binding activity; protein kinase binding activity; and Tau Protein binding activity. Acts upstream of or within several processes, including negative regulation of amyloid precursor protein biosynthetic process; negative regulation of apoptotic signaling pathway; and regulation of mitotic cell cycle. Located in cytoplasm and nucleolus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; liver; and nervous system. Orthologous to human AATF (Apoptosis antagonizing transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Aatf 基因产物(1)

mRNA Protein Name
NM_019816.1 NP_062790.1 protein AATF
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
14627703 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of cell adhesion IMP
IMP: 通过突变表型推断
11071758 MGI
acts upstream of embryonic cleavage IMP
IMP: 通过突变表型推断
11071758 MGI
acts upstream of or within negative regulation of amyloid precursor protein biosynthetic process IDA
IDA: 通过直接分析推断
14627703 MGI
acts upstream of or within negative regulation of apoptotic signaling pathway IGI
IGI: 通过遗传相互作用推断
17488777 MGI
acts upstream of or within regulation of mitotic cell cycle IMP
IMP: 通过突变表型推断
11071758 MGI
acts upstream of or within ribosome biogenesis IMP
IMP: 通过突变表型推断
11071758 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
14627703 MGI
located in nucleolus IDA
IDA: 通过直接分析推断
11071758 MGI
located in nucleus IDA
IDA: 通过直接分析推断
11071758 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
19911006 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

protein AATF

rb-binding protein Che-1

traube protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Aatf NCBI NCBI:26574