2. Gene
  3. Pard6a - par-6 family cell polarity regulator alpha Gene

Pard6a - par-6 family cell polarity regulator alpha Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Par6; Par-6; Par6c; TAX40; PAR-6A; Tip-40; PAR6alpha; 0710008C04Rik; 2610010A15Rik

基因 ID: 56513 | 基因类型: protein coding

关于 Pard6a

功能概要

Enables GTP-dependent protein binding activity and small GTPase binding activity. Involved in cell-cell junction maintenance and positive regulation of protein secretion. Acts upstream of or within negative regulation of protein phosphorylation. Located in several cellular components, including apical part of cell; bicellular tight junction; and cell cortex. Is expressed in several structures, including 2-cell stage conceptus; brain; gut; lung; and reproductive system. Orthologous to human PARD6A (par-6 family cell polarity regulator alpha). [provided by Alliance of Genome Resources, Apr 2022]

Pard6a 基因产物(5)

mRNA Protein Name
NM_001047435.2 NP_001040900.1 partitioning defective 6 homolog alpha isoform 2
NM_001047436.2 NP_001040901.1 partitioning defective 6 homolog alpha isoform 3
NM_001286344.1 NP_001273273.1 partitioning defective 6 homolog alpha isoform 4
NM_001286345.1 NP_001273274.1 partitioning defective 6 homolog alpha isoform 5
NM_019695.3 NP_062669.2 partitioning defective 6 homolog alpha isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GTP-dependent protein binding IPI
IPI: 通过物理相互作用推断
10954424 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10954424 MGI
enables small GTPase binding IDA
IDA: 通过直接分析推断
10954424 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell-cell junction maintenance IDA
IDA: 通过直接分析推断
10954424 MGI
acts upstream of or within negative regulation of protein phosphorylation IGI
IGI: 通过遗传相互作用推断
24305805 MGI
involved in positive regulation of protein secretion IMP
IMP: 通过突变表型推断
27044754 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in bicellular tight junction IDA
IDA: 通过直接分析推断
10954424 MGI
located in cell cortex IDA
IDA: 通过直接分析推断
15028215 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
14685273 MGI
located in nucleus IDA
IDA: 通过直接分析推断
10954424 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

partitioning defective 6 homolog alpha

PAR-6 alpha

Tax interaction protein 40

par-6 (partitioning defective 6,) homolog alpha

Pard6a 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Pard6a Q9Z101 DVL2 Homo sapiens O14641
Anti Tag CoIP
19379695
种属间
Pard6a Q9Z101 DVL2 Homo sapiens O14641
Lumier
19379695
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10038 PARD6A Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pard6a NCBI NCBI:50855
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