1. Gene
  2. Litaf - LPS-induced TN factor Gene

Litaf - LPS-induced TN factor Gene

种属: Mus musculus

同用名: TBX1; N4WBP3; 3222402J11Rik

基因 ID: 56722 | 基因类型: protein coding

关于 Litaf

功能概要

Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; WW domain binding activity; and zinc ion binding activity. Acts upstream of or within cellular response to lipopolysaccharide; negative regulation of NIK/NF-kappaB signaling; and regulation of cytokine production. Predicted to be located in several cellular components, including cytoplasmic side of endosome membrane; cytoplasmic side of lysosomal membrane; and cytoplasmic side of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; retina nuclear layer; and vibrissa. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1C. Orthologous to human LITAF (lipopolysaccharide induced TNF factor). [provided by Alliance of Genome Resources, Apr 2022]

Litaf 基因产物(1)

mRNA Protein Name
NM_019980.2 NP_064364.1 lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11042109 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog

LITAF-like protein

LPS-induced TNF-alpha factor homolog

Nedd4 WW domain-binding protein 3

estrogen-enhanced transcript protein

mEET

Litaf 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Litaf Q9JLJ0 Nedd4 Mus musculus P46935 11042109
种属内
Litaf Q9JLJ0 Nedd4 Mus musculus P46935 11042109
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Litaf NCBI NCBI:9516