LHX9 - LIM homeobox 9 Gene

中文名称：LIM 同源框 9

种属: Homo sapiens

关于 LHX9

功能概要

该基因编码发育表达的转录因子 LIM 同源盒基因家族的成员。编码的蛋白质包含一个同源结构域和两个参与蛋白质-蛋白质相互作用的富含半胱氨酸的锌结合 LIM 结构域。该蛋白质与小鼠蛋白质高度相似，后者在失活时会导致性腺发育不全，表明其在性腺发育中发挥作用。可变剪接导致多个转录本变体。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the LIM homeobox gene family of developmentally expressed transcription factors. The encoded protein contains a homeodomain and two cysteine-rich zinc-binding LIM domains involved in protein-protein interactions. The protein is highly similar to a mouse protein that causes gonadal agenesis when inactivated, suggesting a role in gonadal development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]