PRDM10 - PR/SET domain 10 Gene

中文名称：PR/SET 域 10

种属: Homo sapiens

同用名: PFM7; TRIS

关于 PRDM10

功能概要

该基因编码的蛋白质是一种含有 C2H2 型锌指的转录因子。它还包含一个正调控域，该域已在其他几种锌指转录因子中发现，包括那些参与 B 细胞分化和肿瘤抑制的转录因子。对小鼠对应物的研究表明，这种蛋白质可能参与中枢神经系统 (CNS) 的发育，以及神经元贮积病的发病机制。已经观察到编码不同同种型的多个选择性剪接的转录物变体。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several Other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]