2. Gene
  3. GOPC - golgi associated PDZ and coiled-coil motif containing Gene

GOPC - golgi associated PDZ and coiled-coil motif containing Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含高尔基体相关的 PDZ 和卷曲螺旋基序

种属: Homo sapiens

同用名: CAL; FIG; PIST; GOPC1; dJ94G16.2

基因 ID: 57120 | 基因类型: protein coding

关于 GOPC

Cytogenetic location: 6q22.1 Genomic coordinates (GRCh38): 6:117,560,269-117,602,511 (from NCBI)

This gene has 3 transcripts (splice variants), 215 orthologues and is associated with 55 phenotypes. Ubiquitous expression in thyroid (RPKM 17.5), endometrium (RPKM 15.4) and 25 other tissues.

功能概要

该基因编码具有 PDZ 结构域的高尔基体蛋白。 PDZ 结构域是球状的，包含它们的蛋白质通过靠近 C 末端的短基序与其他蛋白质结合。缺乏直向同源蛋白的小鼠患有圆精子症并且不育。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供，2011 年 12 月]

This gene encodes a Golgi protein with a PDZ domain. The PDZ domain is globular and proteins which contain them bind other proteins through short motifs near the C-termini. Mice which are deficient in the orthologous protein have globozoospermia and are infertile. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

GOPC 基因产物(2)

mRNA Protein Name
NM_001017408.3 NP_001017408.1 Golgi-associated PDZ and coiled-coil motif-containing protein isoform b
NM_020399.4 NP_065132.1 Golgi-associated PDZ and coiled-coil motif-containing protein isoform a

GOPC 蛋白结构

PDZ

PDZ: PDZ domain (Also known as DHR or GLGF) (291 - 367)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 462 a.a.
蛋白主名 其他名称

Golgi-associated PDZ and coiled-coil motif-containing protein

CFTR-associated ligand

重组 GOPC 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73708 PIST Protein, Human (His) Q9HD26 (I286-Y462) ≥95%

关联疾病

疾病名称 别名
Spermatogenic Failure 9

Male Infertility Due To Globozoospermia

SPGF9

Male Infertility Due To Round-Headed Spermatozoa

Globozoospermia, Complete

Globozoospermia, Total

Globozoospermia

Globozoospermia Syndrome

Round-Headed Sperm Syndrome

Globozoospermia Complete

Globozoospermia Total
Acute Laryngitis

Acute Laryngitis Nos

Laryngeal Inflammation

Laryngitis Nos

Larynx Inflammation
Cystic Fibrosis

Mucoviscidosis

CF

Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis

Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis

Cystic Fibrosis Lung Disease, Modifier Of

Cystic Fibrosis Of Pancreas

Fibrocystic Disease Of Pancreas

Cf - [Cystic Fibrosis]

Cystic Fibrosis Nos

Fibrocystic Disease

Fibrocystic Disease Of The Pancreas

Mucoviscidosis Of Pancreas

Nonproliferative Fibrocystic Disease

Pancreatic Cystic Fibrosis
Childhood Angiosarcoma

Paediatric Angiosarcoma

Paediatric Hemangiosarcoma

Pediatric Angiosarcoma

Pediatric Hemangiosarcoma
Glioblastoma

Glioblastoma Multiforme

Gbm

Adult Glioblastoma Multiforme

Grade Iv Adult Astrocytic Tumor

Primary Glioblastoma Multiforme

Spongioblastoma Multiforme

Adult Glioblastoma

Primary Glioblastoma
Osebold-Remondini Syndrome

Brachydactyly Type A6

Brachymesophalangy With Mesomelic Short Limbs And Carpal And Tarsal Osseous Abnormalities

Bda6

Brachydactyly, Type A6
Neonatal Candidiasis

Neonatal Candida Infection

Neonatal Monilia Infection

Neonatal Moniliasis
Sclerosing Hepatic Carcinoma

Sclerosing Hepatocellular Carcinoma
Spermatogenic Failure

Azoospermia

Spgf

Spermatogenic Failure, Susceptibility To

Absent Sperm

Aspermatogenesis

Infertility Due To Azoospermia

Hypospermatogenesis

Azoospermatism
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05599 GOPC Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus GOPC VGNC VGNC:97446
Bos taurus GOPC VGNC VGNC:53793
Mus musculus GOPC MGD MGI:2149946
Rattus norvegicus GOPC RGD RGD:1309512
Canis familiaris GOPC VGNC VGNC:49713
Others GOPC NCBI
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