2. Gene
  3. Zbp1 - Z-DNA binding protein 1 Gene

Zbp1 - Z-DNA binding protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Dai; Dlm1; mZaDLM; 2010010H03Rik

基因 ID: 58203 | 基因类型: protein coding

关于 Zbp1

功能概要

Enables double-stranded RNA binding activity and left-handed Z-DNA binding activity. Involved in several processes, including positive regulation of defense response; positive regulation of programmed cell death; and regulation of interleukin-1-mediated signaling pathway. Acts upstream of or within positive regulation of type I interferon-mediated signaling pathway. Located in cytoplasm and nucleus. Is expressed in eye and heart. Orthologous to human ZBP1 (Z-DNA binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Zbp1 基因产物(2)

mRNA Protein Name
NM_001139519.1 NP_001132991.1 Z-DNA-binding protein 1 isoform 2
NM_021394.2 NP_067369.2 Z-DNA-binding protein 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
17618271 MGI
enables double-stranded RNA binding IDA
IDA: 通过直接分析推断
32200799 MGI
enables left-handed Z-DNA binding IDA
IDA: 通过直接分析推断
11524677 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
22423968 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in activation of innate immune response IDA
IDA: 通过直接分析推断
32200799 MGI
involved in activation of innate immune response IMP
IMP: 通过突变表型推断
32350114 MGI
involved in defense response to fungus IMP
IMP: 通过突变表型推断
33109609 MGI
involved in defense response to virus IDA
IDA: 通过直接分析推断
22423968 MGI
involved in defense response to virus IMP
IMP: 通过突变表型推断
27917412 MGI
involved in positive regulation of apoptotic process IDA
IDA: 通过直接分析推断
27746097 MGI
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
27917412 MGI
involved in positive regulation of inflammatory response IMP
IMP: 通过突变表型推断
27819681 MGI
involved in positive regulation of necroptotic process IDA
IDA: 通过直接分析推断
22423968 MGI
involved in positive regulation of necroptotic process IMP
IMP: 通过突变表型推断
27819681 MGI
acts upstream of or within positive regulation of type I interferon-mediated signaling pathway IMP
IMP: 通过突变表型推断
17618271 MGI
involved in pyroptotic inflammatory response IMP
IMP: 通过突变表型推断
27917412 MGI
involved in regulation of inflammatory response IMP
IMP: 通过突变表型推断
31630209 MGI
involved in regulation of interleukin-1-mediated signaling pathway IMP
IMP: 通过突变表型推断
31630209 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
28607035 MGI
located in nucleus IDA
IDA: 通过直接分析推断
28607035 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

Z-DNA-binding protein 1

DNA-dependent activator of IFN-regulatory factors

tumor stroma and activated macrophage protein DLM-1

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-144873 AVJ16 Inducer 99.60% 否
HY-162424 ZBP1/RIP3/MLKL activator 1 Activator 99.73% 否
HY-RS15958 ZBP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS06619 IGF2BP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16687 Zbp1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16849 Igf2bp1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23122 Zbp1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23290 Igf2bp1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Zbp1 NCBI NCBI:81030
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