2. Gene
  3. Dlc1 - DLC1 Rho GTPase activating protein Gene

Dlc1 - DLC1 Rho GTPase activating protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: RhoGAP; Arhgap7

基因 ID: 58834 | 基因类型: protein coding

关于 Dlc1

功能概要

Enables GTPase activator activity; Phospholipase binding activity; and vinculin binding activity. Involved in activation of Phospholipase C activity; cellular response to Insulin stimulus; and Cytoskeleton organization. Located in membrane raft. Colocalizes with actin filament; focal adhesion; and stress fiber. Human ortholog(s) of this gene implicated in colorectal Cancer. Orthologous to human DLC1 (DLC1 Rho GTPase activating protein). [provided by Alliance of Genome Resources, Apr 2022]

Dlc1 基因产物(2)

mRNA Protein Name
NM_001127446.1 NP_001120918.1 rho GTPase-activating protein 7 isoform 2
NM_001370997.1 NP_001357926.1 rho GTPase-activating protein 7 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GTPase activator activity IDA
IDA: 通过直接分析推断
7835339 RGD
enables phospholipase C activator activity IDA
IDA: 通过直接分析推断
7835339 RGD
enables phospholipase binding IPI
IPI: 通过物理相互作用推断
18157946 RGD
enables vinculin binding IPI
IPI: 通过物理相互作用推断
15506980 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to insulin stimulus IEP
IEP: 通过表达模式推断
16338927 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin filament IDA
IDA: 通过直接分析推断
15506980 RGD
located in focal adhesion IDA
IDA: 通过直接分析推断
15506980 RGD
located in stress fiber IDA
IDA: 通过直接分析推断
15506980 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

rho GTPase-activating protein 7

START domain-containing protein 12

deleted in liver cancer 1 protein homolog

dlc-1

p122-RhoGAP

rho-type GTPase-activating protein 7

stAR-related lipid transfer protein 12

stARD12

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03793 DLC1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS03795 DLEC1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS04088 DYNLL1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19126 Dlc1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25616 Dlc1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dlc1 NCBI NCBI:10395
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