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  2. Cysltr1 - cysteinyl leukotriene receptor 1 Gene

Cysltr1 - cysteinyl leukotriene receptor 1 Gene

中文名称:半胱氨酰白三烯受体 1

种属: Mus musculus

同用名: Cyslt1; CysLT1R

基因 ID: 58861 | 基因类型: protein coding

关于 Cysltr1

Chromosome X: 105,617,952-105,647,285 reverse strand.GRCm39:CM001013.3

This gene has 2 transcripts (splice variants), 177 orthologues, 16 paralogues and is associated with 10 phenotypes. Broad expression in placenta adult (RPKM 1.9), bladder adult (RPKM 1.) and 18 other tissues.

功能概要

该基因编码的蛋白可启动白三烯受体活性。作用于多个过程的上游或内部,包括钙离子运输;趋化性;和对抗原刺激的炎症反应。是质膜的组成部分。在中枢神经系统和视网膜中表达。该基因的人类直系同源物与过敏性疾病有关;哮喘;和鼻炎。与人 CYSLTR1(半胱氨酰白三烯受体 1)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables Leukotriene Receptor activity. Acts upstream of or within several processes, including calcium ion transport; chemotaxis; and inflammatory response to antigenic stimulus. Is integral component of plasma membrane. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in allergic disease; asthma; and rhinitis. Orthologous to human CYSLTR1 (cysteinyl Leukotriene Receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Cysltr1 基因产物(3)

mRNA Protein Name
NM_001281859.1 NP_001268788.1 cysteinyl leukotriene receptor 1 isoform a
NM_001281862.1 NP_001268791.1 cysteinyl leukotriene receptor 1 isoform b
NM_021476.5 NP_067451.2 cysteinyl leukotriene receptor 1 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables leukotriene receptor activity IDA
IDA: 通过直接分析推断
11226226 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
19561298 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within calcium ion transport IDA
IDA: 通过直接分析推断
16002666 MGI
acts upstream of or within cell surface receptor signaling pathway IDA
IDA: 通过直接分析推断
11226226 MGI
acts upstream of or within chemotaxis IDA
IDA: 通过直接分析推断
16002666 MGI
acts upstream of or within establishment of localization in cell IDA
IDA: 通过直接分析推断
16002666 MGI
acts upstream of or within inflammatory response to antigenic stimulus IMP
IMP: 通过突变表型推断
20574000 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
11226226 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Cysltr1 蛋白结构

7tmA_CysLTR1

7tmA_CysLTR1: cd15158 (38 - 65)

7tmA_CysLTR1

7tmA_CysLTR1: cd15158 (38 - 320)

7tmA_CysLTR1

7tmA_CysLTR1: cd15158 (72 - 97)

7tmA_CysLTR1

7tmA_CysLTR1: cd15158 (110 - 140)

7tmA_CysLTR1

7tmA_CysLTR1: cd15158 (152 - 174)

7tmA_CysLTR1

7tmA_CysLTR1: cd15158 (200 - 229)

7tmA_CysLTR1

7tmA_CysLTR1: cd15158 (240 - 270)

7tmA_CysLTR1

7tmA_CysLTR1: cd15158 (288 - 313)

  • 0
  • 100
  • 200
  • 300
  • 352 a.a.
蛋白主名 其他名称

cysteinyl leukotriene receptor 1

LTD4 receptor

cysteinyl leukotriene D4 receptor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cysltr1 NCBI NCBI:10800