1. Gene
  2. F12 - coagulation factor XII (Hageman factor) Gene

F12 - coagulation factor XII (Hageman factor) Gene

种属: Mus musculus

同用名: HAF; FXII

基因 ID: 58992 | 基因类型: protein coding

关于 F12

功能概要

This gene encodes a glycoprotein coagulation factor that plays an important role in the intrinsic pathway of blood coagulation and hemostasis. The encoded protein is an inactive zymogen that is autoactivated upon contact with negatively charged surfaces or misfolded protein aggregates. Mice lacking the encoded protein have a severe defect in forming stable fibrin clots. [provided by RefSeq, Apr 2015]

F12 基因产物(1)

mRNA Protein Name
NM_021489.3 NP_067464.2 coagulation factor XII preproprotein
蛋白主名 其他名称

coagulation factor XII

factor XII

hageman factor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens F12 NCBI NCBI:2161
Canis familiaris F12 NCBI NCBI:489090
Macaca fascicularis F12 NCBI NCBI:101925781
Susscrofa domestica F12 NCBI
Rattus norvegicus F12 NCBI NCBI:306761