2. Gene
  3. RARRES1 - retinoic acid receptor responder 1 Gene

RARRES1 - retinoic acid receptor responder 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：视黄酸受体反应器 1

种属: Homo sapiens

同用名: LXNL; TIG1; PERG-1

基因 ID: 5918 | 基因类型: protein coding

关于 RARRES1

Cytogenetic location: 3q25.32 Genomic coordinates (GRCh38): 3:158,696,892-158,732,457 (from NCBI)

This gene has 5 transcripts (splice variants), 118 orthologues and 1 paralogue. Broad expression in appendix (RPKM 33.7), urinary bladder (RPKM 25.5) and 17 other tissues.

功能概要

该基因被鉴定为视黄酸 (RA) 受体反应基因。它编码 1 型膜蛋白。该基因的表达被他扎罗汀和视黄酸受体上调。发现该基因在前列腺癌中的表达下调，这是由其启动子和 CpG 岛甲基化引起的。已经观察到编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2008 年 7 月]

This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate Cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

RARRES1 基因产物(2)

mRNA Protein Name
NM_002888.4 NP_002879.2 retinoic acid receptor responder protein 1 isoform 2 precursor
NM_206963.2 NP_996846.1 retinoic acid receptor responder protein 1 isoform 1 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21303978 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RARRES1 蛋白结构

Latexin

Latexin: Latexin (52 - 276)

  • 0
  • 100
  • 200
  • 294 a.a.
蛋白主名 其他名称

retinoic acid receptor responder protein 1

RAR-responsive protein TIG1

RARRES1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
RARRES1 P49788 SPINK2 Homo sapiens P20155
Anti Bait CoIP
31886233
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Neurofibroma

Neurofibromas

Neurofibromatoses

Nerve Sheath Tumors
Pinguecula
Conjunctival Degeneration
Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11674 RARRES1 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus RARRES1 RGD RGD:1309509
Bos taurus RARRES1 VGNC VGNC:33731
Canis familiaris RARRES1 VGNC VGNC:45354
Mus musculus RARRES1 MGD MGI:1924461
Macaca mulatta RARRES1 VGNC VGNC:84065
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