2. Gene
  3. Sav1 - salvador family WW domain containing 1 Gene

Sav1 - salvador family WW domain containing 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Sav; Salv; WW45; Wwp3; Wwp4; 1700040G09Rik

基因 ID: 64010 | 基因类型: protein coding

关于 Sav1

功能概要

Predicted to enable several functions, including identical protein binding activity; signaling receptor binding activity; and signaling receptor complex adaptor activity. Acts upstream of or within several processes, including epithelial cell differentiation; hippo signaling; and negative regulation of cell population proliferation. Predicted to be located in cytosol and nucleus. Predicted to be active in cell-cell junction; cytoplasm; and dendrite. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Used to study colonic disease and hepatocellular carcinoma. Orthologous to human SAV1 (salvador family WW domain containing protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Sav1 基因产物(1)

mRNA Protein Name
NM_022028.2 NP_071311.1 protein salvador homolog 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22292086 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of cardiac muscle cell proliferation IMP
IMP: 通过突变表型推断
21512031 MGI
acts upstream of epithelial cell proliferation IMP
IMP: 通过突变表型推断
18369314 MGI
acts upstream of or within hair follicle development IMP
IMP: 通过突变表型推断
18369314 MGI
acts upstream of or within hippo signaling IGI
IGI: 通过遗传相互作用推断
18369314 MGI
acts upstream of or within hippo signaling IMP
IMP: 通过突变表型推断
21512031 MGI
involved in hippo signaling IMP
IMP: 通过突变表型推断
20080689 MGI
acts upstream of or within intestinal epithelial cell differentiation IMP
IMP: 通过突变表型推断
18369314 MGI
acts upstream of keratinocyte apoptotic process IMP
IMP: 通过突变表型推断
18369314 MGI
acts upstream of or within keratinocyte differentiation IGI
IGI: 通过遗传相互作用推断
18369314 MGI
acts upstream of or within keratinocyte differentiation IMP
IMP: 通过突变表型推断
18369314 MGI
acts upstream of or within lung epithelial cell differentiation IMP
IMP: 通过突变表型推断
18369314 MGI
acts upstream of or within negative regulation of cardiac muscle cell proliferation IMP
IMP: 通过突变表型推断
21512031 MGI
acts upstream of or within negative regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
18369314 MGI
acts upstream of or within positive regulation of fat cell differentiation IGI
IGI: 通过遗传相互作用推断
22292086 MGI
acts upstream of or within positive regulation of keratinocyte apoptotic process IMP
IMP: 通过突变表型推断
18369314 MGI
acts upstream of or within regulation of organ growth IMP
IMP: 通过突变表型推断
21512031 MGI
acts upstream of or within regulation of stem cell population maintenance IMP
IMP: 通过突变表型推断
18369314 MGI
acts upstream of or within ventricular septum morphogenesis IMP
IMP: 通过突变表型推断
21512031 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein salvador homolog 1

45 kDa WW domain protein

WW domain-containing protein 3

WW domain-containing protein 4

salvador homolog 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12460 SAV1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18789 Sav1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25278 Sav1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sav1 NCBI NCBI:60485
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