2. Gene
  3. Birc5 - baculoviral IAP repeat-containing 5 Gene

Birc5 - baculoviral IAP repeat-containing 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: AP14

基因 ID: 64041 | 基因类型: protein coding

关于 Birc5

功能概要

Predicted to enable several functions, including chaperone binding activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; and protein dimerization activity. Involved in several processes, including cellular response to ethanol; cellular response to stem cell factor stimulus; and response to glucocorticoid. Located in apical plasma membrane; cytoplasm; and nucleus. Used to study endometriosis and pulmonary hypertension. Biomarker of acute pancreatitis (multiple); artery disease (multiple); congestive heart failure; high grade glioma; and stomach carcinoma. Human ortholog(s) of this gene implicated in prostate Cancer and transitional cell carcinoma. Orthologous to human BIRC5 (baculoviral IAP repeat containing 5). [provided by Alliance of Genome Resources, Apr 2022]

Birc5 基因产物(1)

mRNA Protein Name
NM_022274.2 NP_071610.2 baculoviral IAP repeat-containing protein 5
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to ethanol IEP
IEP: 通过表达模式推断
20610854 RGD
involved in cellular response to stem cell factor stimulus IEP
IEP: 通过表达模式推断
15130521 RGD
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
12833149 RGD
involved in positive regulation of cell cycle IMP
IMP: 通过突变表型推断
18332262 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
17112829 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
17112829 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
17727822 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
17982126 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

baculoviral IAP repeat-containing protein 5

apoptosis inhibitor survivin

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-175352 Nurr1 Agonist 14 / Phase 2
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-173025 Nurr1 agonist 12 Agonist / 否
HY-RS01513 BIRC5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17902 Birc5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24371 Birc5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Birc5 NCBI NCBI:332
Mus musculus Birc5 NCBI NCBI:11799
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