1. Gene
  2. Mre11 - MRE11 homolog, double strand break repair nuclease Gene

Mre11 - MRE11 homolog, double strand break repair nuclease Gene

种属: Rattus norvegicus

同用名: Mre11a

基因 ID: 64046 | 基因类型: protein coding

关于 Mre11

功能概要

Predicted to enable identical protein binding activity; nuclease activity; and protein C-terminus binding activity. Predicted to contribute to DNA binding activity and DNA helicase activity. Involved in heart development and negative regulation of viral entry into host cell. Located in chromatin; nuclear lumen; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in breast carcinoma; endometrial cancer; stomach carcinoma; and urinary bladder Cancer. Orthologous to human MRE11 (MRE11 homolog, double strand break repair nuclease). [provided by Alliance of Genome Resources, Apr 2022]

Mre11 基因产物(2)

mRNA Protein Name
NM_022279.1 NP_071615.1 double-strand break repair protein MRE11
NM_022279.1 NP_071615.1 double-strand break repair protein MRE11
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18212738 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in heart development IEP
IEP: 通过表达模式推断
10908350 RGD
involved in negative regulation of viral entry into host cell IMP
IMP: 通过突变表型推断
22850678 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatin IDA
IDA: 通过直接分析推断
10855503 RGD
located in condensed nuclear chromosome IDA
IDA: 通过直接分析推断
10855503 RGD
located in nucleoplasm IDA
IDA: 通过直接分析推断
16706843 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
18212738 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

double-strand break repair protein MRE11

MRE11 homolog 1

MRE11 homolog A, double strand break repair nuclease

MRE11 homolog, double strand break repair nuclease A

MRE11 meiotic recombination 11 homolog A

double-strand break repair protein MRE11A

meiotic recombination 11 homolog 1

meiotic r

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mre11 NCBI NCBI:4361