2. Gene
  3. Calr - calreticulin Gene

Calr - calreticulin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 64202 | 基因类型: protein coding

关于 Calr

功能概要

Enables several functions, including hormone binding activity; metal ion binding activity; and peptide binding activity. Involved in several processes, including cellular response to lithium ion; response to estradiol; and response to testosterone. Located in several cellular components, including acrosomal vesicle; endoplasmic reticulum; and perinuclear region of cytoplasm. Part of protein-containing complex. Biomarker of vitamin B12 deficiency. Human ortholog(s) of this gene implicated in essential thrombocythemia; myelofibrosis; pancreatic ductal adenocarcinoma; sideroblastic anemia; and thrombocytosis. Orthologous to human CALR (calreticulin). [provided by Alliance of Genome Resources, Apr 2022]

Calr 基因产物(1)

mRNA Protein Name
NM_022399.2 NP_071794.1 calreticulin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium ion binding IDA
IDA: 通过直接分析推断
8500729 RGD
enables hormone binding IPI
IPI: 通过物理相互作用推断
12603316 RGD
enables iron ion binding IDA
IDA: 通过直接分析推断
8500729 RGD
enables mRNA binding IDA
IDA: 通过直接分析推断
14726956 RGD
enables peptide binding IDA
IDA: 通过直接分析推断
10833321 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
22665516 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cardiac muscle cell differentiation IEP
IEP: 通过表达模式推断
9011638 RGD
involved in cellular response to electrical stimulus IEP
IEP: 通过表达模式推断
28428881 RGD
involved in cellular response to lithium ion IEP
IEP: 通过表达模式推断
16236328 RGD
involved in cellular response to virus IEP
IEP: 通过表达模式推断
31399043 RGD
involved in response to biphenyl IEP
IEP: 通过表达模式推断
11452518 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
16339744 RGD
involved in response to glycoside IEP
IEP: 通过表达模式推断
28428881 RGD
involved in response to peptide IEP
IEP: 通过表达模式推断
10833321 RGD
involved in response to testosterone IEP
IEP: 通过表达模式推断
9751517 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
11032977 RGD
involved in spermatogenesis IEP
IEP: 通过表达模式推断
8453984 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in acrosomal vesicle IDA
IDA: 通过直接分析推断
8453984 RGD
located in cell surface IDA
IDA: 通过直接分析推断
11891802 RGD
located in collagen-containing extracellular matrix IDA
IDA: 通过直接分析推断
12782144 RGD
is active in endoplasmic reticulum IDA
IDA: 通过直接分析推断
33239744 RGD
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
18385140 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
12782144 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
33239744 RGD
located in nuclear envelope IDA
IDA: 通过直接分析推断
20607274 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
8600158 RGD
is active in postsynapse IDA
IDA: 通过直接分析推断
33239744 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
12401114 RGD
located in sarcoplasmic reticulum IDA
IDA: 通过直接分析推断
8600158 RGD
located in smooth endoplasmic reticulum IDA
IDA: 通过直接分析推断
22665516 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

calreticulin

CABP3

CALBP

CRP55

ERp60

HACBP

calcium-binding protein 3

calregulin

endoplasmic reticulum resident protein 60

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-14307 Necrocide 1 98.84% 否
HY-176252 CALR ligand 1 Inducer / 否
HY-RS01847 CALR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS01848 CALR3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17947 Calr Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20371 Calr3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24418 Calr Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26881 Calr3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Calr NCBI NCBI:811
Mus musculus Calr NCBI NCBI:12317
Susscrofa domestica Calr NCBI
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