1. Gene
  2. TRA2B - transformer 2 beta homolog Gene

TRA2B - transformer 2 beta homolog Gene

中文名称:变形金刚 2 beta 同系物

种属: Homo sapiens

同用名: SFRS10; SRFS10; TRAN2B; PPP1R156; TRA2-BETA; Htra2-beta

基因 ID: 6434 | 基因类型: protein coding

关于 TRA2B

Cytogenetic location: 3q27.2 Genomic coordinates (GRCh38): 3:185,914,558-185,938,014 (from NCBI)

This gene has 15 transcripts (splice variants), 542 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 41.9), lymph node (RPKM 15.3) and 25 other tissues.

功能概要

该基因编码一种核蛋白,作为序列特异性丝氨酸/精氨酸剪接因子发挥作用,在 mRNA 加工、剪接模式和基因表达中发挥作用。可变剪接导致多个转录本变体。[RefSeq 提供,2011 年 8 月]

This gene encodes a nuclear protein which functions as sequence-specific serine/arginine splicing factor which plays a role in mRNA processing, splicing patterns, and gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

TRA2B 基因产物(2)

mRNA Protein Name
NM_001243879.2 NP_001230808.1 transformer-2 protein homolog beta isoform 2
NM_004593.3 NP_004584.1 transformer-2 protein homolog beta isoform 1

TRA2B 蛋白结构

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (122 - 190)

  • 0
  • 100
  • 200
  • 288 a.a.
蛋白主名 其他名称

transformer-2 protein homolog beta

TRA-2 beta

重组 TRA2B 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72056 TRA2B Protein, Human (Baculovirus, His-Myc) P62995 (S2-Y288) ≥95%

关联疾病

疾病名称 别名
Spinal Muscular Atrophy

Sma

5q Sma

Proximal Sma

Sma-Associated Sma

Spinal Amyotrophies

Spinal Amyotrophy

Spinal Muscle Degeneration

Spinal Muscle Wasting

Muscular Atrophy Spinal

Atrophy, Muscular, Spinal

Hereditary Motor Neuronopathy

Progressive Muscular Atrophy

Sma - [Spinal Muscular Atrophy]

Muscular Atrophy

Muscle Wasting

Amyotrophia

Wasting - Muscle

Skeletal Muscle Atrophy

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris TRA2B VGNC VGNC:47759
Felis catus TRA2B VGNC VGNC:66491
Bos taurus TRA2B VGNC VGNC:36268
Macaca mulatta TRA2B VGNC VGNC:78554
Rattus norvegicus TRA2B RGD RGD:619886
Mus musculus TRA2B MGD MGI:106016
Others TRA2B NCBI