Il12b - interleukin 12B Gene

中文名称：白细胞介素 12B

种属: Rattus norvegicus

同用名: Il12

关于 Il12b

功能概要

该基因编码的蛋白可启动白细胞介素 12 α 亚基结合活性。参与参与免疫反应和疼痛感觉的自然杀伤细胞激活。位于细胞外空间。白细胞介素 12 复合体的一部分。与哮喘有关的该基因的人类直系同源物；慢性阻塞性肺疾病;免疫缺陷 29；和沙门氏菌病。与人 IL12B（白细胞介素 12B）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables interleukin-12 alpha subunit binding activity. Involved in natural killer cell activation involved in immune response and sensory perception of pain. Located in extracellular space. Part of interleukin-12 complex. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; immunodeficiency 29; and salmonellosis. Orthologous to human IL12B (interleukin 12B). [provided by Alliance of Genome Resources, Apr 2022]