2. Gene
  3. Suv39h2 - suppressor of variegation 3-9 2 Gene

Suv39h2 - suppressor of variegation 3-9 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: KMT1B; D2Ertd544e; 4930507K23Rik; D030054H19Rik

基因 ID: 64707 | 基因类型: protein coding

关于 Suv39h2

功能概要

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; chromatin binding activity; and histone-lysine N-methyltransferase activity. Involved in histone H3-K9 methylation; negative regulation of circadian rhythm; and negative regulation of transcription, DNA-templated. Acts upstream of or within histone H3-K9 methylation and male meiotic nuclear division. Located in heterochromatin and nucleus. Is expressed in several structures, including alimentary system; brain; early embryo; genitourinary system; and limb. Orthologous to human SUV39H2 (SUV39H2 histone lysine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Suv39h2 基因产物(1)

mRNA Protein Name
NM_022724.4 NP_073561.2 histone-lysine N-methyltransferase SUV39H2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
21402781 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
11094092 MGI
enables histone H3 methyltransferase activity IDA
IDA: 通过直接分析推断
10949293 MGI
enables histone H3K9 methyltransferase activity IGI
IGI: 通过遗传相互作用推断
15788566 MGI
enables histone H3K9me2 methyltransferase activity IGI
IGI: 通过遗传相互作用推断
23451023 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
24413057 MGI
enables protein methyltransferase activity IDA
IDA: 通过直接分析推断
11094092 MGI
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
24413057 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in circadian rhythm IMP
IMP: 通过突变表型推断
24413057 MGI
involved in male meiotic nuclear division IEP
IEP: 通过表达模式推断
11094092 MGI
involved in negative regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
24413057 MGI
involved in negative regulation of gene expression, epigenetic IMP
IMP: 通过突变表型推断
24413057 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in heterochromatin IDA
IDA: 通过直接分析推断
11094092 MGI
located in nucleus IDA
IDA: 通过直接分析推断
21402781 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

histone-lysine N-methyltransferase SUV39H2

H3-K9-HMTase 2

Suv39h histone methyltransferase

histone H3-K9 methyltransferase 2

su(var)3-9 homolog 2

suppressor of variegation 3-9 homolog 2

相关产品

Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-122181B OTS186935 hydrochloride Inhibitor 99.58% 否
HY-122181 OTS186935 Inhibitor 98.55% 否
HY-13807 UNC0646 Inhibitor 99.38% 否
HY-122182 OTS193320 98.64% 否
HY-148817 WDR5-0102 Inhibitor 97.07% 否
HY-122181A OTS186935 trihydrochloride Inhibitor / 否
HY-RS14052 SUV39H2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18319 Suv39h2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24797 Suv39h2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Suv39h2 NCBI NCBI:79723
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