2. Gene
  3. TMEM135 - transmembrane protein 135 Gene

TMEM135 - transmembrane protein 135 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：跨膜蛋白 135

种属: Homo sapiens

同用名: PMP52

基因 ID: 65084 | 基因类型: protein coding

关于 TMEM135

Cytogenetic location: 11q14.2 Genomic coordinates (GRCh38): 11:87,037,934-87,328,824 (from NCBI)

This gene has 9 transcripts (splice variants), 222 orthologues and is associated with 1 phenotype. Ubiquitous expression in fat (RPKM 8.2), adrenal (RPKM 4.0) and 24 other tissues.

功能概要

预测参与过氧化物酶体组织。预计在对寒冷和对食物的反应之前或之内起作用。预测位于线粒体和过氧化物酶体中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in peroxisome organization. Predicted to act upstream of or within response to cold and response to food. Predicted to be located in mitochondrion and peroxisome. [provided by Alliance of Genome Resources, Apr 2022]

TMEM135 基因产物(2)

mRNA Protein Name
NM_001168724.2 NP_001162195.1 transmembrane protein 135 isoform 2
NM_022918.4 NP_075069.3 transmembrane protein 135 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
33961781 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transmembrane protein 135

peroxisomal membrane protein 52

TMEM135 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TMEM135 Q86UB9 BIRC6 Homo sapiens Q9NR09
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Joubert Syndrome 30

JBTS30

Joubert Syndrome, Type 30
Retinal Dystrophy With Leukodystrophy

RDLKD

Acbd5 Deficiency

Dystrophy, Retinal, With Leukodystrophy
Peroxisomal Biogenesis Disorder

Zellweger Spectrum Disorders

Peroxisome Biogenesis Disorder-Zellweger Syndrome Spectrum

Disorders Of Peroxisome Biogenesis

Zellweger Spectrum

Zellweger Syndrome Spectrum

Peroxisomal Biogenesis Disorders

Pbd, Zss

Pbd-Zsd

Pbd-Zss

Pbd-Zellweger Spectrum Disorder

Peroxisomal Biogenesis Disorders, Zellweger Syndrome Spectrum

Peroxisome Biogenesis Disorder

Peroxisome Biogenesis Disorder Spectrum

Peroxisome Biogenesis Disorders

Zellweger Spectrum Disorder

Hyperpipecolic Acidaemia
Zellweger Syndrome

Cerebrohepatorenal Syndrome

Zellweger Leukodystrophy

Zs

Congenital Iron Overload

Chr

Zws

Severe Pbd-Zsd

Severe Peroxisome Biogenesis Disorder-Zellweger Spectrum Disorder
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14667 TMEM135 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus TMEM135 VGNC VGNC:56288
Canis familiaris TMEM135 VGNC VGNC:47473
Mus musculus TMEM135 MGD MGI:1920009
Felis catus TMEM135 VGNC VGNC:66273
Rattus norvegicus TMEM135 RGD RGD:1309948
Macaca mulatta TMEM135 VGNC VGNC:79585
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