2. Gene
  3. Kcnd3 - potassium voltage-gated channel subfamily D member 3 Gene

Kcnd3 - potassium voltage-gated channel subfamily D member 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Kv4.3

基因 ID: 65195 | 基因类型: protein coding

关于 Kcnd3

功能概要

Enables voltage-gated Potassium Channel activity. Contributes to A-type (transient outward) Potassium Channel activity. Involved in cellular response to BMP stimulus; potassium ion export across plasma membrane; and potassium ion import across plasma membrane. Located in several cellular components, including caveola; neuronal cell body; and perinuclear endoplasmic reticulum. Is integral component of plasma membrane. Part of voltage-gated Potassium Channel complex. Human ortholog(s) of this gene implicated in Brugada syndrome 9 and spinocerebellar ataxia type 19/22. Orthologous to human KCND3 (potassium voltage-gated channel subfamily D member 3). [provided by Alliance of Genome Resources, Apr 2022]

Kcnd3 基因产物(3)

mRNA Protein Name
NM_001270962.1 NP_001257891.1 potassium voltage-gated channel subfamily D member 3 isoform 1 precursor
NM_001270963.1 NP_001257892.1 potassium voltage-gated channel subfamily D member 3 isoform 2 precursor
NM_031739.3 NP_113927.2 potassium voltage-gated channel subfamily D member 3 isoform 3 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables A-type (transient outward) potassium channel activity IDA
IDA: 通过直接分析推断
8831489 RGD
enables A-type (transient outward) potassium channel activity IMP
IMP: 通过突变表型推断
12150935 RGD
enables monoatomic ion channel activity IDA
IDA: 通过直接分析推断
10325948 RGD
enables potassium channel activity IDA
IDA: 通过直接分析推断
10325948 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
10794667 RGD
enables voltage-gated potassium channel activity IDA
IDA: 通过直接分析推断
10325948 RGD
enables voltage-gated potassium channel activity IMP
IMP: 通过突变表型推断
12150935 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to BMP stimulus IMP
IMP: 通过突变表型推断
23747723 RGD
involved in potassium ion export across plasma membrane IDA
IDA: 通过直接分析推断
26016905 RGD
involved in potassium ion import across plasma membrane IDA
IDA: 通过直接分析推断
27198182 RGD
involved in potassium ion transport IDA
IDA: 通过直接分析推断
8831489 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in caveola IDA
IDA: 通过直接分析推断
20224290 RGD
located in dendrite IDA
IDA: 通过直接分析推断
20849929 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
15738276 RGD
located in perinuclear endoplasmic reticulum IDA
IDA: 通过直接分析推断
12967630 RGD
part of voltage-gated potassium channel complex IDA
IDA: 通过直接分析推断
20224290 RGD
part of voltage-gated potassium channel complex IPI
IPI: 通过物理相互作用推断
27198182 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

potassium voltage-gated channel subfamily D member 3

potassium channel, voltage-gated Shal-related subfamily D, member 3

potassium voltage gated channel, Shal-related family, member 3

potassium voltage-gated channel, Shal-related subfamily, member 3

voltage-gated potassium channel subunit Kv4.3

Kcnd3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Kcnd3 Q62897 KCNIP1 Homo sapiens Q9NZI2
Pull Down
17057713
种属间
Kcnd3 Q62897 KCNIP1 Homo sapiens Q9NZI2
X-Ray Diffraction
17057713
种属间
Kcnd3 Q62897 KCNIP1 Homo sapiens Q9NZI2
SAXS
17057713
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07114 KCND3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20972 Kcnd3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27489 Kcnd3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kcnd3 NCBI NCBI:3752
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