2. Gene
  3. Asb2 - ankyrin repeat and SOCS box-containing 2 Gene

Asb2 - ankyrin repeat and SOCS box-containing 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 1110008E15Rik

基因 ID: 65256 | 基因类型: protein coding

关于 Asb2

功能概要

Contributes to ubiquitin protein Ligase activity. Involved in several processes, including heart development; podosome assembly; and skeletal muscle atrophy. Acts upstream of or within cellular protein metabolic process; myoblast differentiation; and skeletal muscle cell differentiation. Located in Z disc. Part of Cul5-RING ubiquitin Ligase complex. Is expressed in several structures, including embryo mesenchyme; genitourinary system; gut; heart; and musculature. Orthologous to human ASB2 (ankyrin repeat and SOCS box containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Asb2 基因产物(2)

mRNA Protein Name
NM_001374764.1 NP_001361693.1 ankyrin repeat and SOCS box protein 2 isoform 2
NM_023049.1 NP_075536.1 ankyrin repeat and SOCS box protein 2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
26343497 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actin cytoskeleton organization IMP
IMP: 通过突变表型推断
29374072 MGI
involved in cardiac muscle cell development IMP
IMP: 通过突变表型推断
29374072 MGI
involved in dendritic cell migration IDA
IDA: 通过直接分析推断
23632887 MGI
involved in heart looping IMP
IMP: 通过突变表型推断
32179481 MGI
involved in podosome assembly IMP
IMP: 通过突变表型推断
23632887 MGI
involved in proteasome-mediated ubiquitin-dependent protein catabolic process IMP
IMP: 通过突变表型推断
23632887 MGI
involved in skeletal muscle atrophy IMP
IMP: 通过突变表型推断
27182554 MGI
acts upstream of or within skeletal muscle cell differentiation IMP
IMP: 通过突变表型推断
22147266 MGI
involved in ubiquitin-dependent protein catabolic process IMP
IMP: 通过突变表型推断
26343497 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Z disc IDA
IDA: 通过直接分析推断
26343497 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ankyrin repeat and SOCS box protein 2

ASB-2

ankyrin repeat and SOCS box-containing protein 2

ankyrin repeat-containing SOCS box protein 2

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-172399 FTO-IN-14 / 否
HY-RS01067 ASB2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22107 Asb2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28628 Asb2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Asb2 NCBI NCBI:51676
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