2. Gene
  3. Exosc3 - exosome component 3 Gene

Exosc3 - exosome component 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Rrp40; 2310005D06Rik

基因 ID: 66362 | 基因类型: protein coding

关于 Exosc3

功能概要

Predicted to enable RNA binding activity. Involved in isotype switching. Acts upstream of or within positive regulation of isotype switching. Predicted to be located in cytoplasm; nuclear lumen; and transcriptionally active chromatin. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1B. Orthologous to human EXOSC3 (exosome component 3). [provided by Alliance of Genome Resources, Apr 2022]

Exosc3 基因产物(2)

mRNA Protein Name
NM_001362788.1 NP_001349717.1 exosome complex component RRP40 isoform 2
NM_025513.4 NP_079789.1 exosome complex component RRP40 isoform 1
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in isotype switching IMP
IMP: 通过突变表型推断
21255825 MGI
acts upstream of or within positive regulation of isotype switching IMP
IMP: 通过突变表型推断
21255825 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

exosome complex component RRP40

exosome complex exonuclease RRP40

ribosomal RNA-processing protein 40

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-139059 ERD03 Inhibitor 99.39% 否
HY-RS04599 EXOSC3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21124 Exosc3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27643 Exosc3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Exosc3 NCBI NCBI:51010
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