2. Gene
  3. Wwp2 - WW domain containing E3 ubiquitin protein ligase 2 Gene

Wwp2 - WW domain containing E3 ubiquitin protein ligase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: AIP2; 1300010O06Rik

基因 ID: 66894 | 基因类型: protein coding

关于 Wwp2

功能概要

Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and ubiquitin protein Ligase activity. Involved in cellular protein metabolic process and regulation of transcription, DNA-templated. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in several structures, including heart valve; respiratory system; sensory organ; skeleton; and tarsus. Orthologous to human WWP2 (WW domain containing E3 ubiquitin protein Ligase 2). [provided by Alliance of Genome Resources, Apr 2022]

Wwp2 基因产物(1)

mRNA Protein Name
NM_025830.4 NP_080106.1 NEDD4-like E3 ubiquitin-protein ligase WWP2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II-specific DNA-binding transcription factor binding IGI
IGI: 通过遗传相互作用推断
21427722 MGI
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
15047715 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21427722 MGI
enables ubiquitin protein ligase activity IDA
IDA: 通过直接分析推断
15047715 MGI
enables ubiquitin-protein transferase activity IDA
IDA: 通过直接分析推断
19997087 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
15047715 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
15047715 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15047715 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
21427722 MGI
involved in proteasome-mediated ubiquitin-dependent protein catabolic process IMP
IMP: 通过突变表型推断
19997087 MGI
involved in protein K63-linked ubiquitination IMP
IMP: 通过突变表型推断
19997087 MGI
involved in protein ubiquitination IDA
IDA: 通过直接分析推断
15047715 MGI
acts upstream of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
21427722 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15047715 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15047715 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

NEDD4-like E3 ubiquitin-protein ligase WWP2

HECT-type E3 ubiquitin transferase WWP2

WW domain-containing protein 2

WW domain-containing protein 4

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-134417 NSC2805 Inhibitor 99.42% 否
HY-168601 WWP1/2-IN-1 Inhibitor / 否
HY-RS15861 WWP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18265 Wwp2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24744 Wwp2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Wwp2 NCBI NCBI:11060
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