1. Gene
  2. Sdhd - succinate dehydrogenase complex, subunit D, integral membrane protein Gene

Sdhd - succinate dehydrogenase complex, subunit D, integral membrane protein Gene

种属: Mus musculus

同用名: QPs3; cybS; CII-4; AVLL5809; PRO19626; 3110001M13Rik

基因 ID: 66925 | 基因类型: protein coding

关于 Sdhd

功能概要

Enables Succinate Dehydrogenase (ubiquinone) activity. Acts upstream of or within cellular response to hypoxia and regulation of Catecholamine secretion. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Carney-Stratakis syndrome; mitochondrial complex II deficiency; paraganglioma; and pheochromocytoma. Orthologous to human SDHD (Succinate Dehydrogenase complex subunit D). [provided by Alliance of Genome Resources, Apr 2022]

Sdhd 基因产物(1)

mRNA Protein Name
NM_025848.3 NP_080124.1 succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables succinate dehydrogenase (quinone) activity IMP
IMP: 通过突变表型推断
15572694 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to hypoxia IMP
IMP: 通过突变表型推断
15572694 MGI
acts upstream of or within regulation of catecholamine secretion IMP
IMP: 通过突变表型推断
15572694 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
16120479 MGI
is active in mitochondrion IMP
IMP: 通过突变表型推断
15572694 MGI
located in mitochondrion IMP
IMP: 通过突变表型推断
15572694 MGI
part of respiratory chain complex II (succinate dehydrogenase) IDA
IDA: 通过直接分析推断
16120479 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial

succinate dehydrogenase complex subunit D

succinate-ubiquinone oxidoreductase cytochrome b small subunit

succinate-ubiquinone reductase membrane anchor subunit

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sdhd NCBI NCBI:6392