2. Gene
  3. Gipc1 - GIPC PDZ domain containing family, member 1 Gene

Gipc1 - GIPC PDZ domain containing family, member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: GIPC; TIP-2; TaxIP2; Semcap1; Glut1CIP; Rgs19ip1

基因 ID: 67903 | 基因类型: protein coding

关于 Gipc1

功能概要

Enables actin binding activity; identical protein binding activity; and Myosin binding activity. Involved in several processes, including negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of transforming growth factor beta receptor signaling pathway; and regulation of synaptic vesicle exocytosis. Acts upstream of or within several processes, including cellular response to interleukin-7; endothelial cell migration; and glutamate secretion. Located in several cellular components, including Schaffer collateral - CA1 synapse; dendrite; and glutamatergic synapse. Is active in postsynapse and presynapse. Is expressed in several structures, including brain; future brain; genitourinary system; hemolymphoid system gland; and sensory organ. Orthologous to human GIPC1 (GIPC PDZ domain containing family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Gipc1 基因产物(1)

mRNA Protein Name
NM_018771.3 NP_061241.1 PDZ domain-containing protein GIPC1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin binding IPI
IPI: 通过物理相互作用推断
15975910 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
15975910 MGI
enables myosin binding IPI
IPI: 通过物理相互作用推断
16908842 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9770488 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to interleukin-7 IDA
IDA: 通过直接分析推断
29581031 MGI
acts upstream of or within chemical synaptic transmission IMP
IMP: 通过突变表型推断
16819522 MGI
acts upstream of or within endothelial cell migration IMP
IMP: 通过突变表型推断
16467373 MGI
acts upstream of or within glutamate secretion IMP
IMP: 通过突变表型推断
16819522 MGI
involved in negative regulation of proteasomal ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
11546783 MGI
involved in positive regulation of transforming growth factor beta receptor signaling pathway IDA
IDA: 通过直接分析推断
11546783 MGI
involved in presynaptic modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
16819522 MGI
involved in presynaptic modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
16819522 MGI
acts upstream of or within protein targeting IMP
IMP: 通过突变表型推断
16467373 MGI
acts upstream of or within protein targeting IPI
IPI: 通过物理相互作用推断
15975910 MGI
involved in regulation of protein stability IDA
IDA: 通过直接分析推断
11546783 MGI
acts upstream of or within regulation of synaptic plasticity IMP
IMP: 通过突变表型推断
16819522 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
16819522 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
16819522 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
16819522 MGI
located in cytosol IDA
IDA: 通过直接分析推断
9770488 MGI
located in dendritic shaft IDA
IDA: 通过直接分析推断
16819522 MGI
located in dendritic spine IDA
IDA: 通过直接分析推断
16819522 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
16819522 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
16819522 MGI
located in membrane IDA
IDA: 通过直接分析推断
9770488 MGI
located in synaptic vesicle IDA
IDA: 通过直接分析推断
16819522 MGI
located in vesicle membrane IDA
IDA: 通过直接分析推断
15975910 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

PDZ domain-containing protein GIPC1

GAIP C-terminus-interacting protein

RGS-GAIP interacting protein GIPC

RGS-GAIP-interacting protein

RGS19-interacting protein 1

SEMCAP-1

Tax interacting protein, clone 2

neurophilin1-IP

regulator of G-protein signaling 19 interacting protein 1

sema

Gipc1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Gipc1 Q9Z0G0 Lrp2 Mus musculus A2ARV4
Pull Down
10827173
种属间
Gipc1 Q9Z0G0 MYO6 Homo sapiens Q9UM54
Anti Tag CoIP
16908842
种属间
Gipc1 Q9Z0G0 MYO6 Homo sapiens Q9UM54
Pull Down
16908842
种属内
Gipc1 Q9Z0G0 Sema4c Mus musculus Q64151
Y2H
10318831
种属内
Gipc1 Q9Z0G0 Sema4c Mus musculus Q64151
Pull Down
10318831
种属内
Gipc1 Q9Z0G0 Sema4c Mus musculus Q64151
Anti Bait CoIP
10318831
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05435 GIPC1 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gipc1 NCBI NCBI:10755
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