2. Gene
  3. Wls - wntless WNT ligand secretion mediator Gene

Wls - wntless WNT ligand secretion mediator Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: EVI; Gpr177; 5031439A09Rik

基因 ID: 68151 | 基因类型: protein coding

关于 Wls

功能概要

Enables Wnt-protein binding activity. Involved in several processes, including animal organ development; mesoderm formation; and positive regulation of canonical Wnt signaling pathway. Located in Golgi apparatus and cytoplasmic vesicle. Is expressed in several structures, including alimentary system; brain; genitourinary system; lung; and skin. Orthologous to human WLS (Wnt ligand secretion mediator). [provided by Alliance of Genome Resources, Apr 2022]

Wls 基因产物(3)

mRNA Protein Name
NM_001356349.1 NP_001343278.1 protein wntless homolog isoform 2 precursor
NM_001356350.1 NP_001343279.1 protein wntless homolog isoform 1
NM_026582.5 NP_080858.3 protein wntless homolog isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Wnt-protein binding IDA
IDA: 通过直接分析推断
19841259 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
19841259 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Wnt protein secretion IDA
IDA: 通过直接分析推断
33324648 MGI
involved in Wnt signaling pathway IMP
IMP: 通过突变表型推断
19841259 MGI
involved in anterior/posterior axis specification IMP
IMP: 通过突变表型推断
19841259 MGI
involved in cementum mineralization IGI
IGI: 通过遗传相互作用推断
31059863 MGI
involved in exocrine pancreas development IMP
IMP: 通过突变表型推断
20614471 MGI
involved in hindbrain development IMP
IMP: 通过突变表型推断
20614471 MGI
involved in mesoderm formation IMP
IMP: 通过突变表型推断
19841259 MGI
involved in midbrain development IMP
IMP: 通过突变表型推断
20614471 MGI
involved in positive regulation of canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
20614471 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
19841259 MGI
located in cytoplasmic vesicle IDA
IDA: 通过直接分析推断
19841259 MGI
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
33324648 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
33324648 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein wntless homolog

G protein-coupled receptor 177

integral membrane protein GPR177

protein evenness interrupted homolog

wntless homolog

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15822 WLS Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22087 Wls Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28607 Wls Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Wls NCBI NCBI:79971
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