1. Gene
  2. Mnx1 - motor neuron and pancreas homeobox 1 Gene

Mnx1 - motor neuron and pancreas homeobox 1 Gene

种属: Rattus norvegicus

同用名: Hlxb9

基因 ID: 682076 | 基因类型: protein coding

关于 Mnx1

功能概要

Predicted to enable sequence-specific double-stranded DNA binding activity. Predicted to be involved in endocrine pancreas development; neuron projection morphogenesis; and spinal cord motor neuron cell fate specification. Predicted to act upstream of or within several processes, including diaphragm development; nervous system development; and pancreas development. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Currarino syndrome. Orthologous to human MNX1 (motor neuron and pancreas homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Mnx1 基因产物(1)

mRNA Protein Name
NM_001271274.1 NP_001258203.1 motor neuron and pancreas homeobox protein 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
18539116 RGD
enables sequence-specific double-stranded DNA binding IDA
IDA: 通过直接分析推断
18539116 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
18539116 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

motor neuron and pancreas homeobox protein 1

homeobox gene HB9

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mnx1 NCBI NCBI:3110