2. Gene
  3. Atp6v1a - ATPase H+ transporting V1 subunit A Gene

Atp6v1a - ATPase H+ transporting V1 subunit A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Atp6v1a1

基因 ID: 685232 | 基因类型: protein coding

关于 Atp6v1a

功能概要

Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in cellular iron ion homeostasis; cellular response to increased oxygen levels; and proton transmembrane transport. Predicted to be located in several cellular components, including apical plasma membrane; microvillus; and secretory granule. Predicted to be part of vacuolar proton-transporting V-type ATPase, V1 domain. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IID and developmental and epileptic encephalopathy 93. Orthologous to human ATP6V1A (ATPase H+ transporting V1 subunit A). [provided by Alliance of Genome Resources, Apr 2022]

Atp6v1a 基因产物(1)

mRNA Protein Name
NM_001108318.2 NP_001101788.1 V-type proton ATPase catalytic subunit A
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32165585 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in extrinsic component of synaptic vesicle membrane EXP
EXP: 通过实验结果推断
32165585 RGD
is active in extrinsic component of synaptic vesicle membrane IDA
IDA: 通过直接分析推断
32165585 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

V-type proton ATPase catalytic subunit A

ATPase, H+ transporting, lysosomal V1 subunit A

Atp6v1a 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Atp6v1a D4A133 q5zww6_legph Legionella pneumophila subsp. pneumophila Q5ZWW6
SLCA
32165585
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-128892 EN6 Activator 99.42% 否
HY-RS29446 ATP6V1A Monkey Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS01223 ATP6V1A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18574 Atp6v1a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25058 Atp6v1a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Atp6v1a NCBI NCBI:523
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